Substance use disorders (SUDs) are complex diseases with biopsychosocial underpinnings and multiple medical sequel that are best addressed by multidisciplinary teams of diverse individuals in the treatment and research realms. This proposal requests continued support of a grant (R25 DA020537) that was used to develop and implement several innovative programs, collectively known as the Drug Abuse Research Training (DART) programs, designed to increase the number of clinician-scientists committed to pursuing clinical research careers in the area of SUDs at the Medical University of South Carolina (MUSC). In the original project period, DART programs targeted psychiatry residents and medical students. In the renewal period, we propose to build on the success of the existing programs by expanding and diversifying the trainees involved in DART programs in strategic directions that align with the priorities of NIDA and the need for interdisciplinary team work that is mandated by the complexities of the patient population with SUDs.
The specific aims of the proposed research education training program are: 1) To continue to attract and train psychiatry residents committed to pursuing research careers focused on patient-oriented research in addictions;2) To transform the DART Summer Research Fellowship for medical students into an interdisciplinary training program by including trainees from the Colleges of Nursing, Dental Medicine and Pharmacy;3) To partner with the existing MUSC Summer Undergraduate Research Program (SURP) to offer a clinical research training experience focused on SUDs to select undergraduate students;4) To partner with the training and training evaluation programs within the MUSC Clinical and Translational Science Institute (UL1 RR029882) so that DART trainees will benefit from CTSA educational resources and addiction research will gain increased visibility across the MUSC campus;5) To conduct targeted outreach to under-represented minority trainees in all of the DART programs. The multidisciplinary training and partnerships with campus-wide training and research initiatives proposed will facilitate the collaborative clinical and research initiatives that will be necessary to meet critical workforce development needs and move the recognition and treatment of addictive disorders into the mainstream of medical practice.

Public Health Relevance

The participation of clinician-scientists in the biomedical research enterprise helps bridge the gap between basic science and clinical practice to address the healthcare needs of the public. In recent years the number of physicians engaged in research careers has declined by more than half, as have the number of research psychiatrists and research fellowships for psychiatrists. Interdisciplinary training focused on substance abuse disorders (SUDs) should facilitate the collaborative clinical and research initiatives that will be necessary to move the recognition and treatment of addictive disorders into mainstream medical practice.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Education Projects (R25)
Project #
5R25DA020537-09
Application #
8653550
Study Section
Special Emphasis Panel (ZDA1-GXM-A (01))
Program Officer
Aklin, Will
Project Start
2006-05-26
Project End
2016-04-30
Budget Start
2014-05-01
Budget End
2015-04-30
Support Year
9
Fiscal Year
2014
Total Cost
$286,179
Indirect Cost
$19,028
Name
Medical University of South Carolina
Department
Psychiatry
Type
Schools of Medicine
DUNS #
183710748
City
Charleston
State
SC
Country
United States
Zip Code
29425
Foster, Katherine T; Li, Ningfei; McClure, Erin A et al. (2016) Gender Differences in Internalizing Symptoms and Suicide Risk Among Men and Women Seeking Treatment for Cannabis Use Disorder from Late Adolescence to Middle Adulthood. J Subst Abuse Treat 66:16-22
Hanlon, Colleen A; Dowdle, Logan T; Moss, Hunter et al. (2016) Mobilization of Medial and Lateral Frontal-Striatal Circuits in Cocaine Users and Controls: An Interleaved TMS/BOLD Functional Connectivity Study. Neuropsychopharmacology 41:3032-3041
Williams, Nolan R; Hopkins, Thomas R; Short, E Baron et al. (2016) Reward circuit DBS improves Parkinson's gait along with severe depression and OCD. Neurocase 22:201-4
Bentzley, Brandon S; Aston-Jones, Gary (2015) Orexin-1 receptor signaling increases motivation for cocaine-associated cues. Eur J Neurosci 41:1149-56
Hanlon, Colleen A; Dowdle, Logan T; Austelle, Christopher W et al. (2015) What goes up, can come down: Novel brain stimulation paradigms may attenuate craving and craving-related neural circuitry in substance dependent individuals. Brain Res 1628:199-209
McClure, Erin A; Lydiard, Jessica B; Goddard, Scott D et al. (2015) Objective and subjective memory ratings in cannabis-dependent adolescents. Am J Addict 24:47-52
Taylor, Joseph J; Williams, Nolan R; George, Mark S (2015) Beyond neural cubism: promoting a multidimensional view of brain disorders by enhancing the integration of neurology and psychiatry in education. Acad Med 90:581-6
Roten, Amanda; Baker, Nathaniel L; Gray, Kevin M (2015) Cognitive performance in a placebo-controlled pharmacotherapy trial for youth with marijuana dependence. Addict Behav 45:119-23
Perkel, Jessica K; Bentzley, Brandon S; Andrzejewski, Matthew E et al. (2015) Delay discounting for sucrose in alcohol-preferring and nonpreferring rats using a sipper tube within-sessions task. Alcohol Clin Exp Res 39:232-8
Sahlem, Gregory L; Badran, Bashar W; Halford, Jonathan J et al. (2015) Oscillating Square Wave Transcranial Direct Current Stimulation (tDCS) Delivered During Slow Wave Sleep Does Not Improve Declarative Memory More Than Sham: A Randomized Sham Controlled Crossover Study. Brain Stimul 8:528-34

Showing the most recent 10 out of 64 publications