The Mount Desert Island Biological Laboratory (MDIBL) and the NIEHS Center for Membrane Toxicity Studies (CMTS) at MDIBL propose a Short-Term Educational Experience for Research (STEER) for six Maine high school students. The overall goal of the MDIBL STEER program is to match selected students with NIEHS Center investigators for a hands-on research experience in the environmental health sciences. The scientific theme is """"""""Pathways of Chemical Action in Human Disease"""""""", which parallels the Center's mission to elucidate the mechanisms of toxicity and pathways of excretion of environmental toxicants at the cellular and molecular level. In addition to the research experience, each student will assemble a fellowship portfolio, including their laboratory notebook, and other components to document their fellowship. Students will participate in external activities to enrich the laboratory experience including journal club meetings, scientific seminars, and presentations. The Center for Research and Evaluation at the University of Maine will conduct program evaluation and analysis, as well as short-term student follow-up. MDIBL will track the educational and career paths of STEER participants beyond their completion of the STEER program. STEER administrators will work with local high school teachers who will nominate students to apply to the program, and who will help MDIBL identify students underrepresented in science by virtue of their ethnicity, race, or individuals from economically or educationally disadvantaged backgrounds.
The specific aims of the MDIBL STEER program are: 1. To provide Maine high school students with multidisciplinary research experiences in the environmental health sciences with applications to human health, mentored by nationally recognized basic scientists and physician scientists and 2. To serve as a pipeline for Maine high school students to continue in undergraduate and graduate degree programs in the environmental health sciences.
The Mount Desert Island Biological Laboratory STEER program pairs select Maine high school students with environmental health scientists in laboratory research around the central theme ?Pathways of Chemical Action in Human Disease.? Using model organisms, students will study human health aspects of environmental exposure;in particular, how normal cellular processes, such as organ function or development, respond to toxic exposures.
|Coffman, James A; Wessels, Abigail; DeSchiffart, Carolyn et al. (2014) Oral-aboral axis specification in the sea urchin embryo, IV: hypoxia radializes embryos by preventing the initial spatialization of nodal activity. Dev Biol 386:302-7|
|Notch, Emily G; Chapline, Chris; Flynn, Erin et al. (2012) Mitogen activated protein kinase 14-1 regulates serum glucocorticoid kinase 1 during seawater acclimation in Atlantic killifish, Fundulus heteroclitus. Comp Biochem Physiol A Mol Integr Physiol 162:443-8|
|Christie, Andrew E; Nolan, Daniel H; Ohno, Paul et al. (2011) Identification of chelicerate neuropeptides using bioinformatics of publicly accessible expressed sequence tags. Gen Comp Endocrinol 170:144-55|
|Christie, Andrew E; Nolan, Daniel H; Garcia, Zachery A et al. (2011) Bioinformatic prediction of arthropod/nematode-like peptides in non-arthropod, non-nematode members of the Ecdysozoa. Gen Comp Endocrinol 170:480-6|
|Coluccio, Alison E; LaCasse, Taylor J; Coffman, James A (2011) Oxygen, pH, and oral-aboral axis specification in the sea urchin embryo. Mol Reprod Dev 78:68|
|Christie, Andrew E; Durkin, Christopher S; Hartline, Niko et al. (2010) Bioinformatic analyses of the publicly accessible crustacean expressed sequence tags (ESTs) reveal numerous novel neuropeptide-encoding precursor proteins, including ones from members of several little studied taxa. Gen Comp Endocrinol 167:164-78|
|Wilson, Caroline H; Christie, Andrew E (2010) Distribution of C-type allatostatin (C-AST)-like immunoreactivity in the central nervous system of the copepod Calanus finmarchicus. Gen Comp Endocrinol 167:252-60|
|Ma, Mingming; Bors, Eleanor K; Dickinson, Evelyn S et al. (2009) Characterization of the Carcinus maenas neuropeptidome by mass spectrometry and functional genomics. Gen Comp Endocrinol 161:320-34|
|Ballatori, Nazzareno; Krance, Suzanne M; Notenboom, Sylvia et al. (2009) Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem 390:191-214|