California State University Los Angeles (Cal State LA) Los Angeles City College, East Los Angeles College, and Pasadena City College have established a very successful collaborative for developing the careers of talented community college science minority students. In the period since last review, 92% of the participating students that completed the program transferred to four-year institutions. We propose continuation of this effort that is making a significant impact on the entry of minority group members into biomedical research careers. We anticipate that at least 80% of the participating community college students will transfer to four-year universities in science majors. This is an ambitious goal as the transfer rate from these community colleges to four-year institutions is some 20% overall. The program we propose for continuation is deliberately designed to: 1) develop student skills in mathematics, basic sciences, and the English language as a foundation to high academic achievement in undergraduate majors in the natural sciences;2) that students are motivated to careers the biomedical sciences through participation in solid research experiences and interaction with science faculty and other biomedical scientists, and;3) that students are prepared for the transition from community college students to upper-division undergraduates at universities. Furthermore, we expect that at least 70% of those who transfer to Cal State LA and get further career development through participation in its MBRS-RISE or MARC U*STAR programs will continue to Ph.D. programs on graduation. Principal Investigator/Program Director (Last, first, middle): Tunstad, Linda

Public Health Relevance

The overarching purpose of our Bridges to the Future effort is to increase the pool of well-prepared community college minority students who pursue biomedically-related majors, and significantly increase their rate of transfer to four-year institutions. This is the first step in a process that will prepare students for success in BS programs, and subsequently the PhD in the biomedical sciences. The proposed project will significantly increase the participation in biomedical research careers by underrepresented minority group members who begin higher education at community colleges, broadening the diversity of intellectual perspectives available to participate in the nation's biomedical research enterprise.

National Institute of Health (NIH)
Education Projects (R25)
Project #
Application #
Study Section
Program Officer
Hamlet, Michelle R
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
California State University Los Angeles
Schools of Arts and Sciences
Los Angeles
United States
Zip Code
Meng, Jia; Kanzaki, Gregory; Meas, Diane et al. (2012) A genome-wide inducible phenotypic screen identifies antisense RNA constructs silencing Escherichia coli essential genes. FEMS Microbiol Lett 329:45-53
Hou, Xiaogang; Suquilanda, Edgar; Zeledon, Ana et al. (2005) Mutations in Sendai virus variant F1-R that correlate with plaque formation in the absence of trypsin. Med Microbiol Immunol 194:129-36
Sun, Xiu Zhu; Vinci, Christopher; Makmura, Linna et al. (2003) Formation of disulfide bond in p53 correlates with inhibition of DNA binding and tetramerization. Antioxid Redox Signal 5:655-65
Furuta, Saori; Ortiz, Fausto; Zhu Sun, Xiu et al. (2002) Copper uptake is required for pyrrolidine dithiocarbamate-mediated oxidation and protein level increase of p53 in cells. Biochem J 365:639-48
Makmura, L; Hamann, M; Areopagita, A et al. (2001) Development of a sensitive assay to detect reversibly oxidized protein cysteine sulfhydryl groups. Antioxid Redox Signal 3:1105-18
Costantino, R F; Cushing, J M; Dennis, B et al. (1998) Resonant population cycles in temporally fluctuating habitats. Bull Math Biol 60:247-73