The objective of the MBRS-IMSD Program at the University of California, Irvine (UCI) is to increase the number and academic excellence of underrepresented (UR) undergraduate and graduate students that complete PhD degrees in biomedical sciences and advance to competitive postdoctoral positions. During the past decade, program increased by severalfold the institutional rate at which UR undergraduates enter PhD programs following graduation and the number of UR graduate students completing PhD programs at UCI. Program elements are academic preparation, research training, intense mentoring and professional development. Independent paid research conducted under the direction of faculty mentors serves as a core element to prepare MBRS students for graduate school and research-focused careers. Research training begins in the freshmen year with the development of original projects that are developed by participants. Over 100 faculty with funded research programs serve as preceptors of MBRS trainees. The program offers a series of components to increase the interest, motivation and academic preparedness of undergraduates (freshmen to seniors) to enter PhD programs in biomedical sciences, including a peer tutoring/mentoring program of science classes, a seminar series, journal club, progress report sessions, workshops on scientific communications, and application to graduate school. The graduate component is designed to provide a comprehensive training for UR Ph.D. students to excel in graduate school. The program provides summer research training for incoming UR PhD students to prepare them for the graduate core classes, a workshop to prepare oral exams after the first year, a series of activities for second year students to prepare a dissertation research project and competitive proposals for extramural funding, presentation of papers at national conferences, professional development workshops on the academic postdoctoral positions search and counseling and orientation about graduate studies and career development in a non-departmental setting.

Public Health Relevance

The inclusion of underrepresented groups in the biomedical scientific workforce is critical to address the need of improving the health of the people of the United States and eliminating health disparities in the nation. This project will improve the quality and number of undergraduate and graduate students from underrepresented groups being trained as the next generation of biomedical research scientists.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
2R25GM055246-17
Application #
8214450
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Janes, Daniel E
Project Start
1996-09-30
Project End
2017-12-31
Budget Start
2013-03-01
Budget End
2013-12-31
Support Year
17
Fiscal Year
2013
Total Cost
$708,788
Indirect Cost
$46,540
Name
University of California Irvine
Department
None
Type
Schools of Arts and Sciences
DUNS #
046705849
City
Irvine
State
CA
Country
United States
Zip Code
92697
Plikus, Maksim V; Guerrero-Juarez, Christian Fernando; Treffeisen, Elsa et al. (2015) Epigenetic control of skin and hair regeneration after wounding. Exp Dermatol 24:167-70
Morgado, Pedro; Sudarshana, Dattanand M; Gov, Lanny et al. (2014) Type II Toxoplasma gondii induction of CD40 on infected macrophages enhances interleukin-12 responses. Infect Immun 82:4047-55
Guerrero-Juarez, Christian Fernando; Ramos, Raul; Oh, Ji Won et al. (2014) Light-emitting hair follicles: studying skin regeneration with in vivo imaging. J Invest Dermatol 134:1496-8
Oh, Ji Won; Hsi, Tsai-Ching; Guerrero-Juarez, Christian Fernando et al. (2013) Organotypic skin culture. J Invest Dermatol 133:e14
Silva, Barbara Alcaraz; Stambaugh, Jessica R; Berns, Michael W (2013) Targeting telomere-containing chromosome ends with a near-infrared femtosecond laser to study the activation of the DNA damage response and DNA damage repair pathways. J Biomed Opt 18:095003
Morgado, Pedro; Ong, Yi-Ching; Boothroyd, John C et al. (2011) Toxoplasma gondii induces B7-2 expression through activation of JNK signal transduction. Infect Immun 79:4401-12
Ma, Christopher; Tran, Johnson; Gu, Frank et al. (2010) Dinitroaniline activity in Toxoplasma gondii expressing wild-type or mutant alpha-tubulin. Antimicrob Agents Chemother 54:1453-60
Gomez-Godinez, Veronica; Wu, Tao; Sherman, Adria J et al. (2010) Analysis of DNA double-strand break response and chromatin structure in mitosis using laser microirradiation. Nucleic Acids Res 38:e202
Kong, Xiangduo; Mohanty, Samarendra K; Stephens, Jared et al. (2009) Comparative analysis of different laser systems to study cellular responses to DNA damage in mammalian cells. Nucleic Acids Res 37:e68
Roca, Alberto I; Almada, Albert E; Abajian, Aaron C (2008) ProfileGrids as a new visual representation of large multiple sequence alignments: a case study of the RecA protein family. BMC Bioinformatics 9:554

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