The MBRS RISE Program at the UPR MSC, currently in its seventh year of support, requests support to continue to expand the overall impact and value of the program. Its overall goal is to increase the number of underrepresented minorities engaged in biomedical and behavioral research, focusing on the development of its undergraduate (UG) and graduate (G) student participants, so they can better compete as future biomedical researchers. We propose three Activities: Developmental Activities 1 &2 - Student Participation in Year Round and Summer Research Programs and Developmental Activity 3: Interdisciplinary Biomedical Research Seminar Series (IBRSS). The following goals and objectives, established for each individual developmental activity, constitute the programmatic goals and objectives of the MSC MBRS RISE program. Programmatic Goal 1: Increase the interest in biomedical research careers, research skills and number of science UG RISE student participants that pursue advanced degrees in biomedical sciences. We will recruit 10 undergraduate science students/year and 15 summer students/year from the UPR System into research projects at the MSC.
We aim to improve the knowledge of the RISE UG participants in biomedical sciences, the principles of Responsible Conduct of Research (RCR), the basics of scientific communication and how to successfully apply to Graduate schools.
We aim to increase the number of UG and G RISE participants that travel to present their research studies and network with other scientists at national or international scientific meetings and engage in short research experiences in mainland US by providing travel funds and the number of UG students that enter graduate programs in the biomedical sciences after finishing their BS degree from 29 to 50%. Our Programmatic Goal #2 is: Increase the interest in research careers, scientific skills and competitiveness and the number of G RISE student participants that complete a Ph.D. degree and advance to competitive postdoctoral positions.
We aim to develop 35 G students by providing financial support and developmental activities that will increase students'skills and competitiveness by improving the knowledge of the G participants in biomedical sciences, the principles of RCR, scientific communication and how to become successful researchers by offering research seminars, scientific writing workshops and instruction on RCR. We propose to increase the number of G students that present at national or international scientific meetings to enhance their scientific communication and networking skills or participate in research experiences outside of the island of Puerto Rico by providing funds for travel to these meetings or for short training experiences and the research productivity of the G students in terms of a 10% increase per year in the average number of publications at peer-reviewed journals and the number of G students who advance to post-doctoral positions from 60% to 80%. Programmatic Goal 3: To enhance the research environment at the UPR-MSC and expose RISE mentors, UG and G students to top biomedical researchers by the establishment of a dynamic Interdisciplinary Biomedical Research Seminar Series (IBRSS). Our objectives are: To increase the exposure of UPR-MSC faculty, UG and G students to state-of-the-art, forefront knowledge in interdisciplinary areas of biomedical sciences by coordinating at least eight annual seminar presentations from different disciplines, with productive biomedical scientists from major research laboratories outside of Puerto Rico;To promote the establishment of associations and networking between UPR-MSC faculty and productive biomedical scientists by stimulating the open discussion of diverse, interdisciplinary research topics in biomedical sciences between UPR-MSC G and UG students and visiting scientists;To improve the comprehension and critical thinking skills of participating students by providing them scientific articles published by invited speakers and promoting the discussion of research findings with the authors and the oral presentation skills of our G students by requiring them to make short presentations in the seminar series. The Minority Biomedical Research Support (MBRS) Program was created in response to a legislative mandate to """"""""increase the numbers of underrepresented minority (URM) faculty, investigators and students engaged in biomedical and behavioral research, and to broaden the opportunities for underrepresented minority faculty and students for participation in biomedical and behavioral research."""""""" The MBRS RISE Program at the UPR MSC, currently in its seventh year of support, requests support to continue to expand the overall impact and value of the program. Its overall goal is to increase the number of underrepresented minorities engaged in biomedical and behavioral research, focusing on the development of its URM undergraduate (UG) and graduate (G) student participants, so they can better compete as future biomedical researchers. We propose three Activities: Developmental Activities 1 &2 - Student Participation in Year Round and Summer Research Programs and Developmental Activity 3: Interdisciplinary Biomedical Research Seminar Series (IBRSS).

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM061838-12
Application #
8133794
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Zlotnik, Hinda
Project Start
2000-09-01
Project End
2012-08-31
Budget Start
2011-09-01
Budget End
2012-08-31
Support Year
12
Fiscal Year
2011
Total Cost
$1,266,885
Indirect Cost
Name
University of Puerto Rico Med Sciences
Department
Biochemistry
Type
Schools of Medicine
DUNS #
948108063
City
San Juan
State
PR
Country
United States
Zip Code
00936
Crespo, Maria J; Roman, Marie; Matias, Jonathan et al. (2018) Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats. Int J Endocrinol 2018:9790303
Rullán-Lind, Carlos; Pietri, Ruth B; Vázquez-Cintrón, Melvin et al. (2018) Fused dimerization increases expression, solubility, and activity of bacterial dehydratase enzymes. Protein Sci 27:969-975
Martínez-Rivera, Freddyson J; Barreto-Estrada, Jennifer L (2018) Reply to: Does High-Frequency Deep Brain Stimulation in Dorsal Regions of the Ventral Striatum Impair Extinction of Morphine-Induced Place Preference? Biol Psychiatry 83:e21
Rivera-Robles, Michael John; Medina-Velázquez, Julia; Asencio-Torres, Gabriela M et al. (2018) Targeting Cdc42 with the anticancer compound MBQ-167 inhibits cell polarity and growth in the budding yeast S. cerevisiae. Small GTPases :1-11
Rosario-Rodríguez, Lester J; Colón, Krystal; Borges-Vélez, Gabriel et al. (2018) Dimethyl Fumarate Prevents HIV-Induced Lysosomal Dysfunction and Cathepsin B Release from Macrophages. J Neuroimmune Pharmacol :
Parodi-Rullán, Rebecca M; Soto-Prado, Jadira; Vega-Lugo, Jesús et al. (2018) Divergent Effects of Cyclophilin-D Inhibition on the Female Rat Heart: Acute Versus Chronic Post-Myocardial Infarction. Cell Physiol Biochem 50:288-303
Parodi-Rullán, Rebecca M; Chapa-Dubocq, Xavier R; Javadov, Sabzali (2018) Acetylation of Mitochondrial Proteins in the Heart: The Role of SIRT3. Front Physiol 9:1094
Maldonado, María Del Mar; Dharmawardhane, Suranganie (2018) Targeting Rac and Cdc42 GTPases in Cancer. Cancer Res 78:3101-3111
Ramírez, Maite; Santos, Saritza; Martínez, Osmarie et al. (2018) Characterization of the immune response elicited by the vaccinia virus L3 protein delivered as naked DNA. Vaccine 36:2049-2055
Ramos-Benitez, Marcos J; Ruiz-Jimenez, Caleb; Rosado-Franco, Jose J et al. (2018) Fh15 Blocks the Lipopolysaccharide-Induced Cytokine Storm While Modulating Peritoneal Macrophage Migration and CD38 Expression within Spleen Macrophages in a Mouse Model of Septic Shock. mSphere 3:

Showing the most recent 10 out of 246 publications