The University of Missouri-Columbia (MU) proposes to identify, provide financial support, and train a total of 28 students from groups dramatically underrepresented in the biomedical sciences in order to prepare them to successfully enter and complete a PhD program in a biomedical or biomedical-related discipline at MU or any other highly competitive research-intensive institution. This proposal presents a coordinated plan to strengthen the research, academic, and personal interaction skills of promising and talented baccalaureate graduates by immersing each Scholar in an independent research project with a faculty mentor and providing a coordinated academic and personal support system. Specific MU PREP components include: design and completion of an independent research project; strong research mentoring by committed faculty, aided by prior training of faculty mentors; training in responsible conduct of research and scientific expression; training in critical thinking and analysis; peer and group mentoring; and presentation of their research results at national/international meetings in the discipline. PREP Scholars should thus begin their PhD programs with advanced research skills, with a faculty and peer mentoring system in place, with connections to a broader discipline beyond MU, and with lasting friendships with other graduate students in the life sciences. The MU PREP program will be carefully coordinated with MU's other undergraduate and PhD programs for underrepresented students thereby advancing MU's comprehensive effort to increase the number of scholars from underrepresented populations in the biomedical sciences. Successful parts of this program will be institutionalized and disseminated as a model for other institutions.

Public Health Relevance

The MU PREP, because of the departments and faculty research mentors involved, will have a natural focus on research training in areas that will address major health problems in the U.S. (e.g. cancer, cardiovascular disease, diabetes and obesity). Of particular interest are health problems that disproportionately affect portions of the U.S. population. This will hopefully lead to greater interest in and research on those health problems at MU, and to a larger number of biomedical researchers working on those problems when our PREP Scholars, and the colleagues they influence, join the biomedical workforce.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
2R25GM064120-14
Application #
9209438
Study Section
NIGMS Initial Review Group (TWD)
Program Officer
Cubano, Luis Angel
Project Start
2002-08-15
Project End
2022-08-31
Budget Start
2017-09-01
Budget End
2018-08-31
Support Year
14
Fiscal Year
2017
Total Cost
Indirect Cost
Name
University of Missouri-Columbia
Department
Biology
Type
Schools of Arts and Sciences
DUNS #
153890272
City
Columbia
State
MO
Country
United States
Zip Code
65211
Nichols, Nicole L; Craig, Taylor A; Tanner, Miles A (2018) Phrenic long-term facilitation following intrapleural CTB-SAP-induced respiratory motor neuron death. Respir Physiol Neurobiol 256:43-49
Villalón, Eric; Barry, Devin M; Byers, Nathan et al. (2018) Internode length is reduced during myelination and remyelination by neurofilament medium phosphorylation in motor axons. Exp Neurol 306:158-168
Johnson, Sarah A; Painter, Michele S; Javurek, Angela B et al. (2017) Characterization of vocalizations emitted in isolation by California mouse (Peromyscus californicus) pups throughout the postnatal period. J Comp Psychol 131:30-39
Allen, James R; Bhattacharyya, Kiran D; Asante, Emilia et al. (2017) Role of branchiomotor neurons in controlling food intake of zebrafish larvae. J Neurogenet 31:128-137
Van Gronigen Caesar, Gerialisa; Dale, Jeffrey M; Osman, Erkan Y et al. (2016) Placental development in a mouse model of spinal muscular atrophy. Biochem Biophys Res Commun 470:82-87
Shababi, Monir; Feng, Zhihua; Villalon, Eric et al. (2016) Rescue of a Mouse Model of Spinal Muscular Atrophy With Respiratory Distress Type 1 by AAV9-IGHMBP2 Is Dose Dependent. Mol Ther 24:855-66
Osman, Erkan Y; Washington 3rd, Charles W; Kaifer, Kevin A et al. (2016) Optimization of Morpholino Antisense Oligonucleotides Targeting the Intronic Repressor Element1 in Spinal Muscular Atrophy. Mol Ther 24:1592-601