This is a program designed to increase the number of post-baccalaureates from currently under-represented groups who become leading biomedical research scientists. It is based on the idea that an enriched hands-on experience in research is the best preparation for PhD training. The training consists of up to two-years in an academic research laboratory apprenticeship pursuing a hypothesis-driven research project. This core experience is complemented with interactive training to increase skills in scientific writing, oral presentation and the critical reading and interpretation of scientific literature. Trainees will be offered additional elective didactic training appropriate to their research project. Collegiality and cooperation will be fostered. The Sackler School of Graduate Biomedical Sciences and Tufts University School of Medicine propose a training plan that will be built on the foundation of well funded and highly regarded research laboratories;highly successful PhD training in biomedical research and several successful training programs that target underrepresented groups. Assessment of the trainees'understanding of their own research, their bench skills, writing skills, presentation technique and leadership skills will be conducted regularly. Evaluation instruments are in place that will provide measurements for fine tuning the training experience. The ultimate success of this PREP training program will be measured by outcomes:
the aim i s to have more than 80% of entering trainees go on to obtain an MD/PhD or PhD from a research-intense school.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM066567-07
Application #
7808877
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Bender, Michael T
Project Start
2002-09-01
Project End
2011-09-14
Budget Start
2010-05-01
Budget End
2011-09-14
Support Year
7
Fiscal Year
2010
Total Cost
$265,401
Indirect Cost
Name
Tufts University
Department
Pathology
Type
Schools of Medicine
DUNS #
039318308
City
Boston
State
MA
Country
United States
Zip Code
02111
Nwankwo, Jennifer O; Gremmel, Thomas; Gerrits, Anja J et al. (2017) Calpain-1 regulates platelet function in a humanized mouse model of sickle cell disease. Thromb Res 160:58-65
de Jesús-Díaz, Dennise A; Murphy, Connor; Sol, Asaf et al. (2017) Host Cell S Phase Restricts Legionella pneumophila Intracellular Replication by Destabilizing the Membrane-Bound Replication Compartment. MBio 8:
McGinty, Ryan J; Puleo, Franco; Aksenova, Anna Y et al. (2017) A Defective mRNA Cleavage and Polyadenylation Complex Facilitates Expansions of Transcribed (GAA)n Repeats Associated with Friedreich's Ataxia. Cell Rep 20:2490-2500
Higashimori, Haruki; Schin, Christina S; Chiang, Ming Sum R et al. (2016) Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo. J Neurosci 36:7079-94
Liang, Liang; Stone, Rivka C; Stojadinovic, Olivera et al. (2016) Integrative analysis of miRNA and mRNA paired expression profiling of primary fibroblast derived from diabetic foot ulcers reveals multiple impaired cellular functions. Wound Repair Regen 24:943-953
Rivas, Hembly G; Schmaling, Summer K; Gaglia, Marta M (2016) Shutoff of Host Gene Expression in Influenza A Virus and Herpesviruses: Similar Mechanisms and Common Themes. Viruses 8:102
Maione, Anna G; Smith, Avi; Kashpur, Olga et al. (2016) Altered ECM deposition by diabetic foot ulcer-derived fibroblasts implicates fibronectin in chronic wound repair. Wound Repair Regen 24:630-43
Uzturk, Belkis Gizem; Jin, Shan-Xue; Rubin, Beverly et al. (2015) RasGRF1 regulates the hypothalamic-pituitary-adrenal axis specifically in early-adolescent female mice. J Endocrinol 227:1-12
Smit, E; Wanke, C; Dong, K et al. (2015) FRAILTY, FOOD INSECURITY, AND NUTRITIONAL STATUS IN PEOPLE LIVING WITH HIV. J Frailty Aging 4:191-7
Campbell, Andrew G; Skvirsky, Rachel; Wortis, Henry et al. (2014) NEST 2014: views from the trainees-talking about what matters in efforts to diversify the STEM workforce. CBE Life Sci Educ 13:587-92

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