The number of underrepresented individuals in the biomedical and behavioral sciences is improving, but more significant increases are still needed. Arizona State University (ASU) Biomedical Post-baccalaureate Research Education Program (PREP) is designed to identify underrepresented baccalaureate graduates with significant potential and commitment to pursue a Ph.D. in these area, but for various reasons do not pursue this goal directly after graduation. ASU Biomedical PREP proposes in this renewal application to continue providing an additional year of preparation beyond the undergraduate degree to help 10 underrepresented graduates smoothly transition into highly competitive biomedical and behavioral graduate programs at ASU and throughout the country. The goal is for participants to successfully complete the Ph.D. and go on to pursue careers as strong investigators in academic or private sectors. The long term goal is to contribute to the development of a strong cohort of scientists that are keenly informed, highly committed and prepared to address important biomedical and behavioral research problems, particularly those that reduce health disparities. The specific goals are to (1) provide a strong intensive individualized mentored research experience, (2) strengthen communication, computational, analytical and critical thinking skills through the research experience, as well as formal and informal activities and (3) provide insight into career options, including information about research focused on elimination of health disparities. PREP students will be recruited from ASU and through contacts with the University of Arizona, Northern Arizona University, and other institutions, especially in California and the Southwest. Students will work with the Director, mentor and other faculty to establish an individualized development plan that focuses on mentored research, academic preparation and skills/training activities to strengthen verbal, analytical and critical thinking skills. Participants will interact with graduate students, postdoctoral fellows and faculty through participation in seminars, journal clubs, lab meetings, local graduate symposia, national meetings and a series of Graduate College programs and activities. PREP will be evaluated on a continuing basis by the Director, Advisory Committee, mentors, evaluators and external advisors.

Public Health Relevance

The goal of PREP is to encourage and help underrepresented individuals successfully complete Ph.D. graduate programs in the biomedical and behavioral sciences. The expectation is that ultimately participants will increase the diversity of active scientists and that some will conduct research in areas that address health disparities.

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Education Projects (R25)
Project #
5R25GM071798-08
Application #
8545865
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Bender, Michael T
Project Start
2004-09-25
Project End
2015-07-31
Budget Start
2013-08-01
Budget End
2014-07-31
Support Year
8
Fiscal Year
2013
Total Cost
$302,143
Indirect Cost
$22,310
Name
Arizona State University-Tempe Campus
Department
Other Health Professions
Type
Organized Research Units
DUNS #
943360412
City
Tempe
State
AZ
Country
United States
Zip Code
85287
Korch, Shaleen B; Malhotra, Vandana; Contreras, Heidi et al. (2015) The Mycobacterium tuberculosis relBE toxin:antitoxin genes are stress-responsive modules that regulate growth through translation inhibition. J Microbiol 53:783-95
Malhotra, Vandana; Agrawal, Ruchi; Duncan, Tammi R et al. (2015) Mycobacterium tuberculosis response regulators, DevR and NarL, interact in vivo and co-regulate gene expression during aerobic nitrate metabolism. J Biol Chem 290:8294-309
Gray, Vanessa E; Liu, Li; Nirankari, Ronika et al. (2014) Signatures of natural selection on mutations of residues with multiple posttranslational modifications. Mol Biol Evol 31:1641-5
Rice, Benjamin L; Acosta, Mónica M; Pacheco, M Andreína et al. (2014) The origin and diversification of the merozoite surface protein 3 (msp3) multi-gene family in Plasmodium vivax and related parasites. Mol Phylogenet Evol 78:172-84
Champion, Mia D; Gray, Vanessa; Eberhard, Carl et al. (2013) The evolutionary history of amino acid variations mediating increased resistance of S. aureus identifies reversion mutations in metabolic regulators. PLoS One 8:e56466
Rice, Benjamin L; Acosta, Mónica M; Pacheco, Maria Andreína et al. (2013) Merozoite surface protein-3 alpha as a genetic marker for epidemiologic studies in Plasmodium vivax: a cautionary note. Malar J 12:288
Kumar, Sudhir; Sanderford, Maxwell; Gray, Vanessa E et al. (2012) Evolutionary diagnosis method for variants in personal exomes. Nat Methods 9:855-6
Malhotra, Vandana; Okon, Blessing P; Clark-Curtiss, Josephine E (2012) Mycobacterium tuberculosis protein kinase K enables growth adaptation through translation control. J Bacteriol 194:4184-96
Gray, Vanessa E; Kukurba, Kimberly R; Kumar, Sudhir (2012) Performance of computational tools in evaluating the functional impact of laboratory-induced amino acid mutations. Bioinformatics 28:2093-6
Claw, Katrina G; Tito, Raul Y; Stone, Anne C et al. (2010) Haplotype structure and divergence at human and chimpanzee serotonin transporter and receptor genes: implications for behavioral disorder association analyses. Mol Biol Evol 27:1518-29

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