The key goal of this application is to increase the numbers of underrepresented students in biomedical and behavioral research by broadening the opportunities to earn Ph.D. degrees and to increase their participation in academic, research, administrative and leadership positions in our country. Northwestern University, an institution with a significant number of mentors with extramural research support, will attract, retain, prepare and facilitate the transition of undergraduate and graduate students of diverse scientific and socio-economic backgrounds into postdoctoral positions in life and biomedical science. We will develop a program to increase the number of graduate students in these areas of science who have the motivation and credentials to succeed, but who lack some of the scientific preparation needed to successfully complete one of the graduate programs at Northwestern University (NUIN, IGP, IBiS, BME, CBE). The strength of the program will be to design an individualized curriculum for each student during the first year in graduate school to overcome academic deficiencies and to allow for successful completion of the specific graduate program core courses during the second year. Course work will be complemented with a scientific skills course, research communication skills workshops, extended research rotations, and faculty and peer-facilitated tutoring and mentoring. Special emphasis will be placed on developing hypothesis-driven research proposals and on writing and presentation skills by attending specialized courses and working with research and communication mentors. This will maximize the opportunities for successful completion of the Ph.D. degree and will increase student competitiveness for external fellowships or appointment to existing training grants (T32). Finally, we will prepare students to transition into competitive postdoctoral research positions and to successfully participate in leadership positions beyond graduation. These goals will be accomplished by requiring students to present their research at local and national meetings, by becoming members of and participating in the activities of scientific societies and by timely publication of scientific findings. We anticipate that the success of the program will be measured by the quality of peer-reviewed publications and presentations at scientific meetings, research and fellowship awards, and successful transition to postdoctoral research and leadership research positions in academia and industry in life and biomedical science areas.

National Institute of Health (NIH)
National Institute of General Medical Sciences (NIGMS)
Education Projects (R25)
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Application #
Study Section
Special Emphasis Panel (ZGM1-MBRS-8 (IM))
Program Officer
Zlotnik, Hinda
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Northwestern University at Chicago
Schools of Medicine
United States
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Dugas, Lara R; Fuller, Miles; Gilbert, Jack et al. (2016) The obese gut microbiome across the epidemiologic transition. Emerg Themes Epidemiol 13:2
Fuller, Miles; Li, Xiaoran; Fisch, Robert et al. (2016) FFA2 Contribution to Gestational Glucose Tolerance Is Not Disrupted by Antibiotics. PLoS One 11:e0167837
Monsivais, Diana; Dyson, Matthew T; Yin, Ping et al. (2016) Estrogen receptor ? regulates endometriotic cell survival through serum and glucocorticoid-regulated kinase activation. Fertil Steril 105:1266-1273
Eastland, Adrienne; Hornick, Jessica; Kawamura, Ryo et al. (2016) Dependence of the structure and mechanics of metaphase chromosomes on oxidized cysteines. Chromosome Res 24:339-53
Ludvik, Anton E; Pusec, Carolina M; Priyadarshini, Medha et al. (2016) HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use. Endocrinology 157:3452-61
Toft, Daniel J; Fuller, Miles; Schipma, Matthew et al. (2016) ?B-crystallin and HspB2 deficiency is protective from diet-induced glucose intolerance. Genom Data 9:10-7
Lambers, Erin; Arnone, Baron; Fatima, Anees et al. (2016) Foxc1 Regulates Early Cardiomyogenesis and Functional Properties of Embryonic Stem Cell Derived Cardiomyocytes. Stem Cells 34:1487-500
Aguiniga, Lizath M; Yaggie, Ryan E; Schaeffer, Anthony J et al. (2016) Lipopolysaccharide Domains Modulate Urovirulence. Infect Immun 84:3131-3140
Dehn, Shirley; DeBerge, Matthew; Yeap, Xin-Yi et al. (2016) HIF-2? in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis. J Immunol 197:3639-3649
Villa, Stephanie R; Priyadarshini, Medha; Fuller, Miles H et al. (2016) Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival. Sci Rep 6:28159

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