There is a critical, national need for an increased number and diversity of health professionals who are actively engaged in clinical and translational research, working to eliminate health disparities and improve minority health. In response to this need, the University of Puerto Rico Medical Sciences Campus, with NIH support (RR017589), has been a leader, having developed and implemented a successful academic program in clinical research, the Master of Science in Clinical Research (MSc) program. To continue and build on our success in increasing the number, quality, and diversity of outstanding Hispanic clinical and translational investigators, we submit this renewal application in response to PAR-11-325, Clinical Research Education and Career Development (CRECD) in Minority Institutions (R25). We propose to expand the availability of current resources to well qualified candidates from partner academic institutions and research centers in Puerto Rico and continue to foster collaborations with US mainland researchers.
The specific aims of this application are: (1) to strengthen research education and career development in Puerto Rico through the implementation of the revised post-doctoral Master of Science in Clinical and Translational Research (MCTR) curriculum;and (2) to develop a diverse group of Hispanic scientists with the necessary knowledge and skills to pursue clinical and translational research, particularly in diseases and healthcare conditions that disproportionately impact minority populations. To further these aims, we propose to strengthen the current post-doctoral program by increasing collaboration with other research training programs, intensifying research mentoring opportunities, and continuing to evaluate our efforts. These enhanced opportunities will ensure that Scholars will participate in on-going faculty research, research seminars, and national conferences. They will also receive publication, presentation, research dissemination, and grantsmanship experiences. We will strengthen the research capacity of the MCTR program through highly trained and experienced faculty and investigators who have productive track records in clinical and translational research in the areas of interest. The formation of thi new generation of clinical and translational investigators will be encouraged by providing administrative, physical, and fiscal support. This Hispanic Clinical and Translational Research Education and Career Development (HCTRECD) program is being further strengthened by fostering partnerships with the community, industry and national research-intensive institutions interested in addressing significant questions in minority health issues. Our ultimate goal is to enhance the participation of minority health professionals in clinical and translational research that will have a significant impact on the health of the community, particularly underrepresented minorities.

Public Health Relevance

The proposed Hispanic Clinical and Translational Research Education and Career Development (HCTRECD) program will help support the efforts of the University of Puerto Rico, Medical Sciences Campus'(UPR-MSC) to increase diversity and the representation of Hispanic clinicians, physicians and scientists well prepared to assume the role of leaders in clinical and translational science that carry out research that address health disparities and improve minority health.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Education Projects (R25)
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Special Emphasis Panel (ZRR1-RI-9 (01))
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Arora, Krishan
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University of Puerto Rico Med Sciences
Schools of Allied Health Profes
San Juan
United States
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Estape, Estela S; Mays, Mary Helen; Sternke, Elizabeth A (2016) Translation in Data Mining to Advance Personalized Medicine for Health Equity. Intell Inf Manag 8:9-16
Leslie, Elizabeth J; Liu, Huan; Carlson, Jenna C et al. (2016) A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3. Am J Hum Genet 98:744-54
Abreu, Orlando J; Tatakis, Dimitris N; Elias-Boneta, Augusto R et al. (2016) Low vitamin D status strongly associated with periodontitis in Puerto Rican adults. BMC Oral Health 16:89
Rivera-Acosta, José E; Aponte, Maysabel; Villamil, Irene et al. (2016) Human Papilloma Virus Awareness Among Hispanic Females with Inflammatory Bowel Disease. J Racial Ethn Health Disparities 3:55-62
Leslie, Elizabeth J; Carlson, Jenna C; Shaffer, John R et al. (2016) A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13. Hum Mol Genet 25:2862-2872
Gowans, L J J; Adeyemo, W L; Eshete, M et al. (2016) Association Studies and Direct DNA Sequencing Implicate Genetic Susceptibility Loci in the Etiology of Nonsyndromic Orofacial Clefts in Sub-Saharan African Populations. J Dent Res 95:1245-56
Castro, Eida M; Jiménez, Julio C; Quinn, Gwendolyn et al. (2015) Identifying clinical and support service resources and network practices for cancer patients and survivors in southern Puerto Rico. Support Care Cancer 23:967-75
Orellano-Colón, Elsa M; Mountain, Gail A; Rosario, Marlene et al. (2015) Environmental Restrictors to Occupational Participation in Old Age: Exploring Differences across Gender in Puerto Rico. Int J Environ Res Public Health 12:11288-303
Rios, R; Estapé, E; Díaz, C et al. (2015) EVALUATION RETREAT: A SENSIBLE METHOD FOR PROGRAM'S ASSESSMENT. INTED Proc 2015:7577-7584
McGinn, Aileen P; Lee, Linda S; Baez, Adriana et al. (2015) Mentoring in Clinical-Translational Research: A Study of Participants in Master's Degree Programs. Clin Transl Sci 8:746-53

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