The proposed CRECD Program at Charles R. Drew University (CDU), Mentored Postdoctoral Training in Translational Research, is a Phase II mentored clinical research and career development program designed to develop a diverse cadre of clinical and translational investigators who conduct innovative research on the underlying causes of diseases, in particular those diseases that disproportionately impact minority populations in the United States (e.g., HIV/AIDS, cancer, cardiovascular disease, diabetes, and mental health/psychiatric disorders), and to foster and facilitate professional development activities in clinical and translational sciences. Over the initial 5-year program period, the CRECD Program will accept a total of eight postdoctoral trainees at the junior faculty level at CDU, each for 3-year appointments, staggered in appointment periods. The CRECD Program will be embedded within the existing, extensive clinical research and training infrastructure at CDU, and thus will mutually leverage resources with other CDU research education and career development programs so as to achieve maximal cross-program synergies as well as efficiencies wrought from utilizing already-in-place education and training curricula and related resources germane to the CRECD agenda. However, the CRECD Program will also carve out a unique niche of training and career development opportunities within the broader CDU science-generating """"""""critical mass"""""""" by (1) focusing exclusively on health disparities and mastery of community-partnered participatory methods in the research and research training agenda and (2) providing to each trainee a first-of-its-kind (at CDU and, by our estimate, nationwide) intensive and community-immersive mentoring configuration that includes CDU faculty from both the standard or conventional Academic Career track and the newly emerging Community Faculty track, called the Partnership for Equity and Equality in Health and Wellness. This intensive mentoring innovation directly emerges from, and formalizes and systematizes into a signature trainee mentoring configuration, a long and fruitful history of community-engaged research, training, and educational curricula at CDU. As an integrated research training and career development package, this approach is designed to bring social determinants of health to the forefront of molecular and clinical research. Ultimately, the goal is to increase the impact of community- academic partnered research and adoption of its evidence-based best practices through comprehensive dissemination of research findings so as to encourage and facilitate implementation of evidence-based treatment and prevention practices within health care organizations and the communities most in need of reliable access to high-quality care.

Public Health Relevance

By providing an outstanding and intensive research mentoring, training, and career development opportunity to minority and other underrepresented postdoctoral scholars in the translational sciences, this new program at Charles Drew University will increase the diversity of the scientific workforce and develop next-generation clinical and translational investigators who conduct innovative research on the underlying causes of diseases, in particular those diseases that disproportionately impact minority populations in the United States.

National Institute of Health (NIH)
National Institute on Minority Health and Health Disparities (NIMHD)
Education Projects (R25)
Project #
Application #
Study Section
Special Emphasis Panel (ZRR1-RI-9 (01))
Program Officer
Arora, Krishan
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
Charles R. Drew University of Medicine & Science
Family Medicine
Schools of Medicine
Los Angeles
United States
Zip Code
Gelfand, Robert; Vernet, Dolores; Bruhn, Kevin et al. (2016) Long-term exposure of MCF-12A normal human breast epithelial cells to ethanol induces epithelial mesenchymal transition and oncogenic features. Int J Oncol 48:2399-414
Bazargan, Mohsen; Yazdanshenas, Hamed; Gordon, David et al. (2016) Pain in Community-Dwelling Elderly African Americans. J Aging Health 28:403-25
Yazdanshenas, Hamed; Bazargan, Mohsen; Jones, Loretta et al. (2016) Engaging Gatekeeper-Stakeholders in Development of a Mobile Health Intervention to Improve Medication Adherence Among African American and Pacific Islander Elderly Patients With Hypertension. JMIR Mhealth Uhealth 4:e116
Chung, Seyung S; Oliva, Bryant; Dwabe, Sami et al. (2016) Combination treatment with flavonoid morin and telomerase inhibitor MST‑312 reduces cancer stem cell traits by targeting STAT3 and telomerase. Int J Oncol 49:487-98
Yazdanshenas, Hamed; Ashouri, Anousheh; Kaufman, Galen (2016) Neurovestibular Compensation following Ototoxic Lesion and Labyrinthectomy. Int Arch Otorhinolaryngol 20:114-23
Kusnezov, Nicholas A; Yazdanshenas, Hamed; Garcia, Eddie et al. (2016) Epidemiology of musculoskeletal injury in the California film and motion picture industry. Rev Environ Health 31:251-7
Madadi, Firooz; Madadi, Firoozeh; Maleki, Arash et al. (2016) A new method for tibial torsion measurement by computerized tomography. J Orthop 13:43-7
Bazargan, Mohsen; Yazdanshenas, Hamed; Han, Shelley et al. (2016) Inappropriate Medication Use Among Underserved Elderly African Americans. J Aging Health 28:118-38
Wu, Yanyuan; Sarkissyan, Marianna; Vadgama, Jaydutt V (2016) Epithelial-Mesenchymal Transition and Breast Cancer. J Clin Med 5:
Yazdanshenas, Hamed; Bazargan, Mohsen; Smith, James et al. (2016) Pain Treatment of Underserved Older African Americans. J Am Geriatr Soc 64:2116-2121

Showing the most recent 10 out of 26 publications