This R25 application is organized around two overall themes-building bridges between basic and clinical research and building bridges between science and clinical service. We plan to develop further the infrastructure needed to conduct clinical research training within the frameworks of both translational and public health models. A key premise of our program is the importance of forging links between neuroscience, neuroimaging, and genetics and their applications to interventions with psychiatric and physical illnesses throughout the lifespan. We also plan to build bridges between the tradition we have established of treatment outcome research done in controlled clinical trials and the current priority accorded by NIMH to intervention research with an increased public health orientation.
Our specific aims i nclude: (1) development of a Junior Faculty Scholars Program that will provide 25 percent salary support for two years to faculty members selected competitively by the Executive Committee of our Research Education and Training Center (RETC). The short-term goal is to facilitate the development of K-award career development applications by these faculty; the long-term goal is to ensure their success as independent investigators doing clinical research; (2) development of a curriculum with two tracks-one for translational research and a second for intervention research. Both tracks will involve one mini-course during the academic year (10 sessions) and two intensive summer workshops (one week each); (3) provision of four awards for pilot research studies by Junior Faculty Scholars collecting initial data in support of their K-award applications; and (4) hiring of one full-time statistician who will provide support to the Junior Faculty Scholars. Issues regarding recruitment of underrepresented minorities and women are addressed, and specific criteria for evaluating the success of the program (e.g., an increase in funded early career development awards and mid-career patient-oriented research awards) are also described.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Education Projects (R25)
Project #
5R25MH060473-02
Application #
6187623
Study Section
Special Emphasis Panel (ZMH1-CRB-J (03))
Program Officer
Wynne, Debra K
Project Start
1999-09-23
Project End
2004-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
2
Fiscal Year
2000
Total Cost
$248,961
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
Martin, Elizabeth A; Siegle, Greg J; Steinhauer, Stuart R et al. (2018) Timing matters in elaborative processing of positive stimuli: Gamma band reactivity in schizophrenia compared to depression and healthy adults. Schizophr Res :
Khalaf, Alexander; Edelman, Kathryn; Tudorascu, Dana et al. (2015) White Matter Hyperintensity Accumulation During Treatment of Late-Life Depression. Neuropsychopharmacology 40:3027-35
Mandell, Darcy; Siegle, Greg J; Shutt, Luann et al. (2014) Neural substrates of trait ruminations in depression. J Abnorm Psychol 123:35-48
Cruz, Mario; Roter, Debra L; Cruz, Robyn F et al. (2013) Appointment length, psychiatrists' communication behaviors, and medication management appointment adherence. Psychiatr Serv 64:886-92
Castillo, Enrico G; Pincus, Harold A; Wieland, Melissa et al. (2012) Communication profiles of psychiatric residents and attending physicians in medication-management appointments: a quantitative pilot study. Acad Psychiatry 36:96-103
Morse, Jennifer Q; Shaffer, David R; Williamson, Gail M et al. (2012) Models of self and others and their relation to positive and negative caregiving responses. Psychol Aging 27:211-8
Maalouf, Fadi T; Clark, Luke; Tavitian, Lucy et al. (2012) Bias to negative emotions: a depression state-dependent marker in adolescent major depressive disorder. Psychiatry Res 198:28-33
Sit, Dorothy; Perel, James M; Wisniewski, Stephen R et al. (2011) Mother-infant antidepressant concentrations, maternal depression, and perinatal events. J Clin Psychiatry 72:994-1001
Siegle, Greg J; Steinhauer, Stuart R; Friedman, Edward S et al. (2011) Remission prognosis for cognitive therapy for recurrent depression using the pupil: utility and neural correlates. Biol Psychiatry 69:726-33
Cruz, Mario; Roter, Debra; Cruz, Robyn Flaum et al. (2011) Psychiatrist-patient verbal and nonverbal communications during split-treatment appointments. Psychiatr Serv 62:1361-8

Showing the most recent 10 out of 77 publications