This proposal is a competitive renewal application for The Brown Initiative in HIV and AIDS Clinical Research for Disadvantaged Communities, currently funded through NIMH R25MH083620. Our goal is to train the next generation of minority researchers to address the challenges of prevention, diagnosis and treatment of HIV, particularly in minority communities. Nearly 50% of new infections are among African-Americans, and African-Americans have poorer health outcomes at every point along the HIV/AIDS continuum of diagnosis and care. In particular, African American communities, particularly the inner-city Eastern seaboard and the rural and urban South, are most heavily impacted by HIV/AIDS. President Obama's National AIDS Strategy calls for reduction in HIV incidence, reductions in racial disparities in HIV infection, and allocating resources to the most heavily impacted communities. In order to address racial disparities in HIV infection and the impact of HIV/AIDS in minority communities, we must train minority investigators from the most heavily impacted communities, particularly from inner city communities and the American South. This requires interdisciplinary, culturally competent research training of the next generation of HIV/AIDS researchers;this training must address the social, structural and behavioral factors contributing to the epidemic. The Brown Initiative in HIV and AIDS Clinical Research for Disadvantaged Communities is an educational and mentoring program for new investigators from underrepresented racial and ethnic groups, with a particular focus on African Americans conducting research on HIV/AIDS health disparities and the co-occurring epidemics of incarceration, hepatitis C co-infection, substance use, and mental illness. During our first five years, we trained 28 minority postdoctoral and junior faculty members in HIV related clinical research, and developed collaborative relationships with five universities, with an emphasis on Mississippi and the South. Scholars from diverse disciplines represent 14 institutions;79% of scholars are African- American, 11% are Asian Pacific Islander, 7% are Hispanic, and 3% are Native American. This proposal includes a stronger focus on community-engaged research.
We aim to train the next cadre of investigators to conduct interdisciplinary research that responds to the social, behavioral and structural factors that contribute to racial disparities in HIV infectio in the most heavily impacted communities of the US, particularly in the South and in inner city settings. We gauge success of our initiative through abstracts, manuscripts, independent grant funding, faculty positions, and meaningful participation in community-engaged research.

Public Health Relevance

This proposal is a competitive renewal application for The Brown Initiative in HIV and AIDS Clinical Research for Disadvantaged Communities, currently funded through NIMH R25MH083620. The goal is to train the next generation of clinical researchers from disadvantaged backgrounds to address the challenges of prevention, diagnosis and treatment of HIV, particularly in the minority communities.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Education Projects (R25)
Project #
2R25MH083620-06A1
Application #
8603548
Study Section
Special Emphasis Panel (ZMH1-ERB-M (05))
Program Officer
Stoff, David M
Project Start
2008-04-01
Project End
2019-07-31
Budget Start
2014-09-08
Budget End
2015-07-31
Support Year
6
Fiscal Year
2014
Total Cost
$256,805
Indirect Cost
$14,942
Name
Miriam Hospital
Department
Type
DUNS #
063902704
City
Providence
State
RI
Country
United States
Zip Code
02906
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Touzard Romo, F; Smeaton, L M; Campbell, T B et al. (2014) Renal and metabolic toxicities following initiation of HIV-1 treatment regimen in a diverse, multinational setting: a focused safety analysis of ACTG PEARLS (A5175). HIV Clin Trials 15:246-60
Temple, Brian; Conteh, Sulaimin (2013) "The second rule". J Miss State Med Assoc 54:25-6
Nunn, Amy; Zaller, Nickolas; Cornwall, Alexandra et al. (2011) Low perceived risk and high HIV prevalence among a predominantly African American population participating in Philadelphia's Rapid HIV testing program. AIDS Patient Care STDS 25:229-35
Temple, Brian; Kwara, Awewura; Sunesara, Imran et al. (2011) Factors associated with recently transmitted Mycobacterium tuberculosis strain MS0006 in Hinds County, Mississippi. South Med J 104:819-26
Flanigan, Timothy P; Payne, Nanetta; Simmons, Emma et al. (2009) Lessons learned from a training collaboration between an Ivy League institution and a historically Black university. Am J Public Health 99 Suppl 1:S57-60