Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
7R29AG013623-02
Application #
2001766
Study Section
Neurology A Study Section (NEUA)
Project Start
1995-09-01
Project End
2000-08-31
Budget Start
1996-04-08
Budget End
1996-08-31
Support Year
2
Fiscal Year
1995
Total Cost
Indirect Cost
Name
Allegheny University of Health Sciences
Department
Neurology
Type
Schools of Medicine
DUNS #
City
Philadelphia
State
PA
Country
United States
Zip Code
19129
Ishii, K; Lippa, C; Tomiyama, T et al. (2001) Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition. Neurobiol Aging 22:367-76
Lippa, C F; Swearer, J M; Kane, K J et al. (2000) Familial Alzheimer's disease: site of mutation influences clinical phenotype. Ann Neurol 48:376-9
Lippa, C F (1999) Familial Alzheimer's disease: genetic influences on the disease process (Review). Int J Mol Med 4:529-36
Lippa, C F; Schmidt, M L; Lee, V M et al. (1999) Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease. Ann Neurol 45:353-7
Nee, L E; Lippa, C F (1999) Alzheimer's disease in 22 twin pairs--13-year follow-up: hormonal, infectious and traumatic factors. Dement Geriatr Cogn Disord 10:148-51
Lippa, C F; Smith, T W; Perry, E (1999) Dementia with Lewy bodies: choline acetyltransferase parallels nucleus basalis pathology. J Neural Transm 106:525-35
Lippa, C F; Johnson, R; Smith, T W (1998) The medial temporal lobe in dementia with Lewy bodies: a comparative study with Alzheimer's disease. Ann Neurol 43:102-6
Lippa, C F; Fujiwara, H; Mann, D M et al. (1998) Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. Am J Pathol 153:1365-70
Lippa, C F; Nee, L E; Mori, H et al. (1998) Abeta-42 deposition precedes other changes in PS-1 Alzheimer's disease. Lancet 352:1117-8
Lippa, C F; Smith, T W; Saunders, A M et al. (1997) Apolipoprotein E-epsilon 2 and Alzheimer's disease: genotype influences pathologic phenotype. Neurology 48:515-9

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