Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29CA049017-02
Application #
3459267
Study Section
Radiation Study Section (RAD)
Project Start
1989-01-01
Project End
1993-12-31
Budget Start
1990-01-01
Budget End
1990-12-31
Support Year
2
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Harvard University
Department
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Palayoor, S T; Macklis, R M; Bump, E A et al. (1995) Modulation of radiation-induced apoptosis and G2/M block in murine T-lymphoma cells. Radiat Res 141:235-43
Humm, J L; Macklis, R M; Lu, X Q et al. (1995) The spatial accuracy of cellular dose estimates obtained from 3D reconstructed serial tissue autoradiographs. Phys Med Biol 40:163-80
Humm, J L; Macklis, R M; Yang, Y et al. (1994) Image analysis for the study of radionuclide distribution in tissue sections. J Nucl Med 35:1217-25
Macklis, R M; Beresford, B A; Humm, J L (1994) Radiobiologic studies of low-dose-rate 90Y-lymphoma therapy. Cancer 73:966-73
Palayoor, S T; Humm, J L; Atcher, R W et al. (1993) G2M arrest and apoptosis in murine T lymphoma cells following exposure to 212Bi alpha particle irradiation. Nucl Med Biol 20:795-805
Macklis, R M (1993) Magnetic healing, quackery, and the debate about the health effects of electromagnetic fields. Ann Intern Med 118:376-83
Macklis, R M; Beresford, B A; Palayoor, S et al. (1993) Cell cycle alterations, apoptosis, and response to low-dose-rate radioimmunotherapy in lymphoma cells. Int J Radiat Oncol Biol Phys 27:643-50
Humm, J L; Macklis, R M; Bump, K et al. (1993) Internal dosimetry using data derived from autoradiographs. J Nucl Med 34:1811-7
Speidel, M T; Holmquist, B; Kassis, A I et al. (1993) Morphological, biochemical, and molecular changes in endothelial cells after alpha-particle irradiation. Radiat Res 136:373-81
Macklis, R M; Lin, J Y; Beresford, B et al. (1992) Cellular kinetics, dosimetry, and radiobiology of alpha-particle radioimmunotherapy: induction of apoptosis. Radiat Res 130:220-6

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