The purpose of this project is to describe the encoding of speech sound differences in the human cerebral cortex, specifically, the nature of early acoustic-phonetic analyses that map acoustic cues onto abstract phonetic representations of speech sounds. The methodology involves coupling behavioral testing with two well-established clinical techniques: direct cortical electrical interference and intracarotid sodium amobarbital testing. Preliminary studies confirmed the efficacy of this approach, established a critical role for cortical processing in speech discrimination, and provided the foundation for three working hypotheses: (1) Cortical encoding is differentially sensitive to consonant-vowel, but not to traditional consonant feature differences; (2) Acoustic-phonetic analyses for speech discrimination are also required for auditory access to lexical processing; and (3) Cortical regions critical for speech discrimination are highly localized with lateral left perisylvian cortex. The proposed studies will assist in determining the scope of cortical sensitivity to acoustic-phonetic information and in identifying critical underlying neuroanatomic structures.

Agency
National Institute of Health (NIH)
Institute
National Institute on Deafness and Other Communication Disorders (NIDCD)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29DC003081-04
Application #
6175393
Study Section
Special Emphasis Panel (ZRG1-SEN (06))
Program Officer
Shekim, Lana O
Project Start
1997-07-01
Project End
2002-06-30
Budget Start
2000-07-01
Budget End
2001-06-30
Support Year
4
Fiscal Year
2000
Total Cost
$110,902
Indirect Cost
Name
Johns Hopkins University
Department
Neurology
Type
Schools of Medicine
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
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