Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29GM050263-03
Application #
2187968
Study Section
Experimental Virology Study Section (EVR)
Project Start
1994-01-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Wisconsin Madison
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
161202122
City
Madison
State
WI
Country
United States
Zip Code
53715
Liu, Ning; Tian, Ru; Loeb, Daniel D (2003) Base pairing among three cis-acting sequences contributes to template switching during hepadnavirus reverse transcription. Proc Natl Acad Sci U S A 100:1984-9
Mueller-Hill, Karlyn; Loeb, Daniel D (2002) cis-Acting sequences 5E, M, and 3E interact to contribute to primer translocation and circularization during reverse transcription of avian hepadnavirus DNA. J Virol 76:4260-6
Loeb, Daniel D; Mack, Amanda A; Tian, Ru (2002) A secondary structure that contains the 5' and 3' splice sites suppresses splicing of duck hepatitis B virus pregenomic RNA. J Virol 76:10195-202
Havert, Michael B; Ji, Lin; Loeb, Daniel D (2002) Analysis of duck hepatitis B virus reverse transcription indicates a common mechanism for the two template switches during plus-strand DNA synthesis. J Virol 76:2763-9
Loeb, D D; Tian, R (2001) Mutations that increase in situ priming also decrease circularization for duck hepatitis B virus. J Virol 75:6492-7
Loeb, D D; Tian, R; Gulya, K J et al. (1998) Changing the site of initiation of plus-strand DNA synthesis inhibits the subsequent template switch during replication of a hepadnavirus. J Virol 72:6565-73
Jiang, H; Loeb, D D (1997) Insertions within epsilon affect synthesis of minus-strand DNA before the template switch for duck hepatitis B virus. J Virol 71:5345-54
Loeb, D D; Gulya, K J; Tian, R (1997) Sequence identity of the terminal redundancies on the minus-strand DNA template is necessary but not sufficient for the template switch during hepadnavirus plus-strand DNA synthesis. J Virol 71:152-60
Havert, M B; Loeb, D D (1997) cis-Acting sequences in addition to donor and acceptor sites are required for template switching during synthesis of plus-strand DNA for duck hepatitis B virus. J Virol 71:5336-44
Mueller-Hill, K; Loeb, D D (1996) Previously unsuspected cis-acting sequences for DNA replication revealed by characterization of a chimeric heron/duck hepatitis B virus. J Virol 70:8310-7

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