The investigator will examine the impact of life events and social support on the course of bipolar disorder. Life events and social support have been shown to have substantial impact on the course of other psychiatric disorders. Although theoretical and clinical articles have suggested that life events and social support will contribute to bipolar disorder, these domains have received only limited empirical attention. Much of the research on life events within this disorder has had methodological limitations, and no research has examined the ability of social support to buffer life events. The investigator will examine the effects of life events and social support using a naturalistic, prospective design. One-hundred and seventy-five Bipolar I patients will be recruited during an index episode. Symptom patterns and treatment will be assessed once a month for 2 years. Life events and social support will be assessed using comprehensive interview-based measures at 2-, 6-, 12-, 18-, and 24-month followups. Primary analyses will examine the impact of life events and social support on time to recovery and relapse. A secondary goal of the study will be to increase knowledge of social support within bipolar disorder. The current investigation will examine the influence of previous episodes, degree of recovery, and self-esteem on social support. A long-term goal of the study will be to develop a bi- directional model of the social support-illness relationship. Overall, the current investigation is expected to yield information about the role of life events and social support on recovery and relapse in bipolar disorder.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
First Independent Research Support & Transition (FIRST) Awards (R29)
Project #
5R29MH055950-03
Application #
2416182
Study Section
Clinical Psychopathology Review Committee (CPP)
Project Start
1995-09-30
Project End
2000-04-30
Budget Start
1997-05-15
Budget End
1998-04-30
Support Year
3
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Miami Coral Gables
Department
Psychology
Type
Schools of Arts and Sciences
DUNS #
City
Coral Gables
State
FL
Country
United States
Zip Code
33146
Gershon, A; Johnson, S L; Miller, I (2013) Chronic stressors and trauma: prospective influences on the course of bipolar disorder. Psychol Med 43:2583-92
Johnson, Sheri L; Fulford, Daniel (2008) Development of the treatment attitudes questionnaire in bipolar disorder. J Clin Psychol 64:466-81
Miller, Ivan W; Keitner, Gabor I; Ryan, Christine E et al. (2008) Family treatment for bipolar disorder: family impairment by treatment interactions. J Clin Psychiatry 69:732-40
Johnson, Sheri L; Cuellar, Amy K; Cueller, Amy K et al. (2008) Life events as predictors of mania and depression in bipolar I disorder. J Abnorm Psychol 117:268-77
Meyer, Bjorn; Beevers, Christopher G; Johnson, Sheri L et al. (2007) Unique association of approach motivation and mania vulnerability. Cogn Emot 21:1647
Perlman, Carol A; Johnson, Sheri L; Mellman, Thomas A (2006) The prospective impact of sleep duration on depression and mania. Bipolar Disord 8:271-4
Johnson, S L; Meyer, B; Winett, C et al. (2000) Social support and self-esteem predict changes in bipolar depression but not mania. J Affect Disord 58:79-86
Greenhouse, W J; Meyer, B; Johnson, S L (2000) Coping and medication adherence in bipolar disorder. J Affect Disord 59:237-41
Johnson, S L; Sandrow, D; Meyer, B et al. (2000) Increases in manic symptoms after life events involving goal attainment. J Abnorm Psychol 109:721-7
Johnson, S L; Winett, C A; Meyer, B et al. (1999) Social support and the course of bipolar disorder. J Abnorm Psychol 108:558-66