The UNLV American Indian Research and Education Center propose a community-based, participatory, translational research study entitled """"""""Life in BALANCE"""""""" (Balancing Actions, Lifestyle, Autonomy, Nutrition, Community, &Environment). This two-year planning project will be a prelude to a large-scale, multi-site, cohort study of effective diabetes prevention among urban (nonreservation) American Indians/Alaska Natives. Research is needed to fully understand behavioral intervention, barriers to health care, cost effective diabetes prevention, education, and self-management and the social, cultural, and political mechanisms that create disparities in this underserved population. The study will apply the Diabetes Prevention Program (DPP) intensive """"""""lifestyle coaching"""""""" clinical research intervention with the goal of improving modifiable risk factors, to ultimately achieve good glucose control, and prevent diabetes complications. American Indians/Alaska Natives living in urban settings are at high risk for diabetes and its complications but have not benefited from the body of research conducted in tribal communities. Planning for a project of this scope will include: 1) establishment of a strong community-based research infrastructure to guide development of translational research and a large scale clinical trial;and 2) conduct a pilot study with the urban Indian population in Southern Nevada. This study will provide knowledge and information regarding strategies for diabetes prevention and provide a foundation for future research.

Public Health Relevance

This project is highly relevant to public health. Type 2 diabetes accounts for about 90- 95% of all diagnosed cases of diabetes (NDEP) and AI/AN on average are 2.2 times more likely to have diabetes as non-Hispanics whites. While diabetes care and prevention has been advanced in reservation-based populations, little is known about effective strategies for urban Indians, who constitute an estimate 60% of the total AI/AN population in the US.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Planning Grant (R34)
Project #
1R34DK080258-01A2
Application #
7659230
Study Section
Special Emphasis Panel (ZDK1-GRB-1 (J1))
Program Officer
Garfield, Sanford A
Project Start
2009-04-01
Project End
2011-03-31
Budget Start
2009-04-01
Budget End
2010-03-31
Support Year
1
Fiscal Year
2009
Total Cost
$215,813
Indirect Cost
Name
University of Nevada Las Vegas
Department
Type
Schools of Public Health
DUNS #
098377336
City
Las Vegas
State
NV
Country
United States
Zip Code
89154
Benyshek, Daniel C; Chino, Michelle; Dodge-Francis, Carolee et al. (2013) Prevention of type 2 diabetes in urban American Indian/Alaskan Native communities: The Life in BALANCE pilot study. J Diabetes Mellitus 3:184-191