The implementation of the MMT program in China is one of the most significant measures ever taken by the Chinese government to tackle drug use and HIV prevention challenges, and the effectiveness of these programs has implications for HIV and drug use control. Several pilot studies have identified high client drop-out rate, insufficient training of service providers and limited client service as the main challenges these programs face. We propose to take this window of opportunity to address these challenges by developing and testing an intervention, MMT PLUS, to be added on to the current MMT standard care in China. The proposed MMT PLUS intervention is designed primarily for service providers who work at MMT clinics. The proposed intervention pilot will take 2.5 years and proceed in two phases in Sichuan, China. In Phase 1, we will develop intervention manuals and supporting materials, and finalize assessment measures and implementation procedures. We will also recruit and train staff, establish quality assurance procedures and data encryption and data transfer processes. In Phase 2, we will conduct the pilot intervention across 6 MMT clinics involving 30 service providers and 150 MMT clients, and follow up at 3, 6, and 9-month period. The service provider outcomes are adherence to MMT protocol, reduction in prejudicial attitude toward MMT clients, increase in comfort working with MMT clients, and increase in motivating clients and making personalized risk management plan. The client outcomes are increased motivation to change, improved psychological and physical health, increased positive support network, and reduced HIV risk behavior.

Public Health Relevance

China CDC, the collaborating agency for this study, is the leading force in implementing the current MMT program and has committed to develop new, innovative MMT models for nation-wide dissemination. The findings of this pilot could provide benefits for China and beyond by advancing the field through the sharing of our experience and the lessons learned in integrating a behavioral intervention into a primarily pharmacological model of methadone maintenance, and in transferring timely program development findings to country-wide implementation and policy-making.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Planning Grant (R34)
Project #
5R34MH083512-02
Application #
7778845
Study Section
Special Emphasis Panel (ZMH1-ERB-E (05))
Program Officer
Pequegnat, Willo
Project Start
2009-03-02
Project End
2012-02-29
Budget Start
2010-03-01
Budget End
2011-02-28
Support Year
2
Fiscal Year
2010
Total Cost
$260,416
Indirect Cost
Name
University of California Los Angeles
Department
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Li, Li; Wu, Zunyou; Liang, Li-Jung et al. (2013) An intervention targeting service providers and clients for methadone maintenance treatment in China: a cluster-randomized trial. Addiction 108:356-66
Li, Li; Lin, Chunqing; Wan, Dai et al. (2012) Concurrent heroin use among methadone maintenance clients in China. Addict Behav 37:264-8
Li, Li; Wu, Zunyou; Cao, Xiaobin et al. (2012) Provider-Client Interaction in Methadone Treatment Clinics in China. J Drug Issues 42:
Li, Li; Ding, Yingying; Lai, Wenhong et al. (2011) Motivational profiles of clients seeking methadone maintenance therapy in China. Drug Alcohol Depend 118:335-40