I propose to continue along the path of my prior work in cancer epidemiology. That work will entail: 1) Analyses of routinely-collected data on cancer incidence. Local and national data will be used, both to generate clues as to the etiologies of cancer and to address practical issues of cancer prevention. 2) Cohort and population-based case-control studies of cancer. In addition to concluding a number of studies begun during the first cycle of funding from the Outstanding Investigator Grant, I plan to initiate others, likely including studies of: a) ovarian cancer in relation to galactose consumption and metabolism; and b) subsequent cancer incidence among women with infertility, with particular attention given to the type of infertility and its treatment. With colleagues in the laboratory, I will continue to explore ways of more precisely characterizing exposure or susceptibility that can be put to use in epidemiologic studies. 3) Refinement of epidemiologic methods relevant to the study of cancer. Emphasis will be given to development of analytic strategies to minimize bias in case-control studies which evaluate the efficacy of cancer screening modalities.

Agency
National Institute of Health (NIH)
Institute
National Cancer Institute (NCI)
Type
Unknown (R35)
Project #
5R35CA039779-13
Application #
2376786
Study Section
Special Emphasis Panel (SRC (88))
Project Start
1985-07-01
Project End
1999-02-28
Budget Start
1997-03-01
Budget End
1998-02-28
Support Year
13
Fiscal Year
1997
Total Cost
Indirect Cost
Name
University of Washington
Department
Public Health & Prev Medicine
Type
Schools of Public Health
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Prescott, Jennifer; Setiawan, Veronica W; Wentzensen, Nicolas et al. (2015) Body Mass Index Genetic Risk Score and Endometrial Cancer Risk. PLoS One 10:e0143256
Felix, Ashley S; Gaudet, Mia M; La Vecchia, Carlo et al. (2015) Intrauterine devices and endometrial cancer risk: a pooled analysis of the Epidemiology of Endometrial Cancer Consortium. Int J Cancer 136:E410-22
Cote, Michele L; Alhajj, Tala; Ruterbusch, Julie J et al. (2015) Risk factors for endometrial cancer in black and white women: a pooled analysis from the Epidemiology of Endometrial Cancer Consortium (E2C2). Cancer Causes Control 26:287-296
Chen, Maxine M; Crous-Bou, Marta; Setiawan, Veronica W et al. (2014) Exome-wide association study of endometrial cancer in a multiethnic population. PLoS One 9:e97045
Setiawan, Veronica Wendy; Schumacher, Fredrick; Prescott, Jennifer et al. (2014) Cross-cancer pleiotropic analysis of endometrial cancer: PAGE and E2C2 consortia. Carcinogenesis 35:2068-73
Kamineni, Aruna; Weinmann, Sheila; Shy, Kirkwood K et al. (2013) Efficacy of screening in preventing cervical cancer among older women. Cancer Causes Control 24:1653-60
Setiawan, Veronica Wendy; Yang, Hannah P; Pike, Malcolm C et al. (2013) Type I and II endometrial cancers: have they different risk factors? J Clin Oncol 31:2607-18
Phipps, Amanda I; Doherty, Jennifer A; Voigt, Lynda F et al. (2011) Long-term use of continuous-combined estrogen-progestin hormone therapy and risk of endometrial cancer. Cancer Causes Control 22:1639-46
Pocobelli, Gaia; Doherty, Jennifer A; Voigt, Lynda F et al. (2011) Pregnancy history and risk of endometrial cancer. Epidemiology 22:638-45
Doherty, Jennifer A; Weiss, Noel S; Fish, Sherianne et al. (2011) Polymorphisms in nucleotide excision repair genes and endometrial cancer risk. Cancer Epidemiol Biomarkers Prev 20:1873-82

Showing the most recent 10 out of 128 publications