Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AA011156-05
Application #
6227426
Study Section
Special Emphasis Panel (NSS)
Project Start
1996-09-30
Project End
2004-08-31
Budget Start
2000-09-01
Budget End
2001-08-31
Support Year
5
Fiscal Year
2000
Total Cost
$259,930
Indirect Cost
Name
University of Colorado at Boulder
Department
Genetics
Type
Other Domestic Higher Education
DUNS #
City
Boulder
State
CO
Country
United States
Zip Code
80309
Bowers, Barbara J; McClure-Begley, Tristan D; Keller, Jason J et al. (2005) Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol. Alcohol Clin Exp Res 29:295-302
Butt, Christopher M; King, Nathan M; Hutton, Scott R et al. (2005) Modulation of nicotine but not ethanol preference by the mouse Chrna4 A529T polymorphism. Behav Neurosci 119:26-37
Salminen, Outi; Whiteaker, Paul; Grady, Sharon R et al. (2005) The subunit composition and pharmacology of alpha-Conotoxin MII-binding nicotinic acetylcholine receptors studied by a novel membrane-binding assay. Neuropharmacology 48:696-705
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Butt, Christopher M; Hutton, Scott R; Stitzel, Jerry A et al. (2003) A polymorphism in the alpha4 nicotinic receptor gene (Chrna4) modulates enhancement of nicotinic receptor function by ethanol. Alcohol Clin Exp Res 27:733-42
Owens, Jeremy C; Balogh, Seth A; McClure-Begley, Tristan D et al. (2003) Alpha 4 beta 2* nicotinic acetylcholine receptors modulate the effects of ethanol and nicotine on the acoustic startle response. Alcohol Clin Exp Res 27:1867-75
Balogh, Seth A; Owens, Jeremy C; Butt, Christopher M et al. (2002) Animal models as a tool for studying mechanisms of co-abuse of alcohol and tobacco. Alcohol Clin Exp Res 26:1911-4
Dobelis, Peter; Marks, Michael J; Whiteaker, Paul et al. (2002) A polymorphism in the mouse neuronal alpha4 nicotinic receptor subunit results in an alteration in receptor function. Mol Pharmacol 62:334-42
Butt, Christopher M; Hutton, Scott R; Marks, Michael J et al. (2002) Bovine serum albumin enhances nicotinic acetylcholine receptor function in mouse thalamic synaptosomes. J Neurochem 83:48-56
Tritto, Theresa; Stitzel, Jerry A; Marks, Michael J et al. (2002) Variability in response to nicotine in the LSxSS RI strains: potential role of polymorphisms in alpha4 and alpha6 nicotinic receptor genes. Pharmacogenetics 12:197-208

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