Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
1R37AG006060-01A1
Application #
3480113
Study Section
Neurology A Study Section (NEUA)
Project Start
1986-08-01
Project End
1991-07-31
Budget Start
1986-08-01
Budget End
1987-07-31
Support Year
1
Fiscal Year
1986
Total Cost
Indirect Cost

  Institution

Name
University of Rochester
Department
Type
Schools of Medicine
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

ThyagaRajan, Srinivasan; Felten, David L (2002) Modulation of neuroendocrine--immune signaling by L-deprenyl and L-desmethyldeprenyl in aging and mammary cancer. Mech Ageing Dev 123:1065-79
ThyagaRajan, S; Madden, K S; Stevens, S Y et al. (2000) Restoration of splenic noradrenergic nerve fibers and immune reactivity in old F344 rats: a comparison between L-deprenyl and L-desmethyldeprenyl. Int J Immunopharmacol 22:523-36
Felten, D L (2000) Neural influence on immune responses: underlying suppositions and basic principles of neural-immune signaling. Prog Brain Res 122:381-9
ThyagaRajan, S; Madden, K S; Stevens, S Y et al. (1999) Effects of L-deprenyl treatment on noradrenergic innervation and immune reactivity in lymphoid organs of young F344 rats. J Neuroimmunol 96:57-65
ThyagaRajan, S; Stevens, S Y; Felten, D L (1999) Region-specific alterations in the concentrations of catecholamines and indoleamines in the brains of young and old F344 rats after L-deprenyl treatment. Brain Res Bull 48:513-20
ThyagaRajan, S; Madden, K S; Kalvass, J C et al. (1998) L-deprenyl-induced increase in IL-2 and NK cell activity accompanies restoration of noradrenergic nerve fibers in the spleens of old F344 rats. J Neuroimmunol 92:9-21
ThyagaRajan, S; Felten, S Y; Felten, D L (1998) Restoration of sympathetic noradrenergic nerve fibers in the spleen by low doses of L-deprenyl treatment in young sympathectomized and old Fischer 344 rats. J Neuroimmunol 81:144-57
Felten, D L; Felten, S Y; Fuller, R W et al. (1992) Chronic dietary pergolide preserves nigrostriatal neuronal integrity in aged-Fischer-344 rats. Neurobiol Aging 13:339-51
Felten, D L; Felten, S Y; Steece-Collier, K et al. (1992) Age-related decline in the dopaminergic nigrostriatal system: the oxidative hypothesis and protective strategies. Ann Neurol 32 Suppl:S133-6
Date, I; Notter, M F; Felten, S Y et al. (1991) Stereotaxic injection of GD1a ganglioside induces limited recovery of striatal dopaminergic system in MPTP-treated aging mice. J Neurosci Res 28:525-30

Showing the most recent 10 out of 15 publications