Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AG011728-11
Application #
6690749
Study Section
Cell Development and Function Integrated Review Group (CDF)
Program Officer
Mccormick, Anna M
Project Start
1993-09-20
Project End
2004-10-31
Budget Start
2004-01-01
Budget End
2004-10-31
Support Year
11
Fiscal Year
2004
Total Cost
$338,625
Indirect Cost
Name
Baylor College of Medicine
Department
Genetics
Type
Schools of Medicine
DUNS #
051113330
City
Houston
State
TX
Country
United States
Zip Code
77030
Rao, Timsi; Lubin, Johnathan W; Armstrong, Geoffrey S et al. (2014) Structure of Est3 reveals a bimodal surface with differential roles in telomere replication. Proc Natl Acad Sci U S A 111:214-8
Tucey, Timothy M; Lundblad, Victoria (2014) Regulated assembly and disassembly of the yeast telomerase quaternary complex. Genes Dev 28:2077-89
Lubin, Johnathan W; Rao, Timsi; Mandell, Edward K et al. (2013) Dissecting protein function: an efficient protocol for identifying separation-of-function mutations that encode structurally stable proteins. Genetics 193:715-25
Tucey, Timothy M; Lundblad, Victoria (2013) A yeast telomerase complex containing the Est1 recruitment protein is assembled early in the cell cycle. Biochemistry 52:1131-3
Ballew, Bari J; Lundblad, Victoria (2013) Multiple genetic pathways regulate replicative senescence in telomerase-deficient yeast. Aging Cell 12:719-27
(2013) Correction to A Yeast Telomerase Complex Containing the Est1 Recruitment Protein Is Assembled Early in the Cell Cycle Biochemistry 52:5027
Lundblad, Victoria (2012) Telomere end processing: unexpected complexity at the end game. Genes Dev 26:1123-7
Lubin, Johnathan W; Tucey, Timothy M; Lundblad, Victoria (2012) The interaction between the yeast telomerase RNA and the Est1 protein requires three structural elements. RNA 18:1597-604
Paschini, Margherita; Mandell, Edward K; Lundblad, Victoria (2010) Structure prediction-driven genetics in Saccharomyces cerevisiae identifies an interface between the t-RPA proteins Stn1 and Ten1. Genetics 185:11-21
Lee, Jaesung; Mandell, Edward K; Rao, Timsi et al. (2010) Investigating the role of the Est3 protein in yeast telomere replication. Nucleic Acids Res 38:2279-90

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