In the very limited space available (8 pages) for the continuation of our R37 grant we will (a) briefly describe our plans for a 3 year retention assessment ofthe older advlt subjects who participated in our previous 1 year (3 one hour training sessions per week for a year) randomized fitness training intervention trial and (b) provide a more deteuled description of our plans for a novel randomized traiiung intervention that we believe capitalizes on what we have learned from our previous intervention as well as other training interventions, with older adults, that have taken place over the past several years (e.g. ACTIVE, Willis et al, 2006;Experience Corps, Carlson et al, in press, video game training, Basak et al., 2008). Given the page limitations, we do not provide extensive methodological details in this abbreviated proposal and hope that our previous experience -with the methods and kinds of training protocols we have proposed will satisfy any concerns.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Method to Extend Research in Time (MERIT) Award (R37)
Project #
Application #
Study Section
No Study Section (in-house review) (NSS)
Program Officer
Wagster, Molly V
Project Start
Project End
Budget Start
Budget End
Support Year
Fiscal Year
Total Cost
Indirect Cost
University of Illinois Urbana-Champaign
Schools of Arts and Sciences
United States
Zip Code
Zuniga, Krystle E; Mackenzie, Michael J; Kramer, Arthur et al. (2016) Subjective memory impairment and well-being in community-dwelling older adults. Psychogeriatrics 16:20-6
Burzynska, A Z; Wong, C N; Chaddock-Heyman, L et al. (2016) White matter integrity, hippocampal volume, and cognitive performance of a world-famous nonagenarian track-and-field athlete. Neurocase 22:135-44
Nagamatsu, Lindsay S; Weinstein, Andrea M; Erickson, Kirk I et al. (2016) Exercise Mode Moderates the Relationship Between Mobility and Basal Ganglia Volume in Healthy Older Adults. J Am Geriatr Soc 64:102-8
Cooke, Gillian E; Wetter, Nathan C; Banducci, Sarah E et al. (2016) Moderate Physical Activity Mediates the Association between White Matter Lesion Volume and Memory Recall in Breast Cancer Survivors. PLoS One 11:e0149552
Oberlin, Lauren E; Verstynen, Timothy D; Burzynska, Agnieszka Z et al. (2016) White matter microstructure mediates the relationship between cardiorespiratory fitness and spatial working memory in older adults. Neuroimage 131:91-101
Voss, Michelle W; Weng, Timothy B; Burzynska, Agnieszka Z et al. (2016) Fitness, but not physical activity, is related to functional integrity of brain networks associated with aging. Neuroimage 131:113-25
Mackenzie, Michael J; Zuniga, Krystle E; Raine, Lauren B et al. (2016) Associations Between Physical Fitness Indices and Working Memory in Breast Cancer Survivors and Age-Matched Controls. J Womens Health (Larchmt) 25:99-108
Burzynska, Agnieszka Z; Wong, Chelsea N; Voss, Michelle W et al. (2015) White matter integrity supports BOLD signal variability and cognitive performance in the aging human brain. PLoS One 10:e0120315
Awick, Elizabeth A; Wójcicki, Thomas R; Olson, Erin A et al. (2015) Differential exercise effects on quality of life and health-related quality of life in older adults: a randomized controlled trial. Qual Life Res 24:455-62
Zuniga, K; McAuley, E (2015) Considerations in selection of diet assessment methods for examining the effect of nutrition on cognition. J Nutr Health Aging 19:333-40

Showing the most recent 10 out of 68 publications