Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI012464-27
Application #
6510081
Study Section
Special Emphasis Panel (NSS)
Program Officer
Meegan, James M
Project Start
1987-04-01
Project End
2006-02-28
Budget Start
2002-03-01
Budget End
2003-02-28
Support Year
27
Fiscal Year
2002
Total Cost
$398,049
Indirect Cost
Name
University of Alabama Birmingham
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
004514360
City
Birmingham
State
AL
Country
United States
Zip Code
35294
Mondal, Arindam; Victor, Ken G; Pudupakam, R S et al. (2014) Newly identified phosphorylation site in the vesicular stomatitis virus P protein is required for viral RNA synthesis. J Virol 88:1461-72
Harouaka, Djamila; Wertz, Gail W (2012) Second-site mutations selected in transcriptional regulatory sequences compensate for engineered mutations in the vesicular stomatitis virus nucleocapsid protein. J Virol 86:11266-75
Rainsford, Edward W; Harouaka, Djamila; Wertz, Gail W (2010) Importance of hydrogen bond contacts between the N protein and RNA genome of vesicular stomatitis virus in encapsidation and RNA synthesis. J Virol 84:1741-51
Harouaka, Djamila; Wertz, Gail W (2009) Mutations in the C-terminal loop of the nucleocapsid protein affect vesicular stomatitis virus RNA replication and transcription differentially. J Virol 83:11429-39
Galloway, Summer E; Wertz, Gail W (2009) A temperature sensitive VSV identifies L protein residues that affect transcription but not replication. Virology 388:286-93
Hinzman, Edward E; Barr, John N; Wertz, Gail W (2008) Selection for gene junction sequences important for VSV transcription. Virology 380:379-87
Galloway, Summer E; Wertz, Gail W (2008) S-adenosyl homocysteine-induced hyperpolyadenylation of vesicular stomatitis virus mRNA requires the methyltransferase activity of L protein. J Virol 82:12280-90
Barr, John N (2007) Bunyavirus mRNA synthesis is coupled to translation to prevent premature transcription termination. RNA 13:731-6
Green, Todd J; Zhang, Xin; Wertz, Gail W et al. (2006) Structure of the vesicular stomatitis virus nucleoprotein-RNA complex. Science 313:357-60
Martinez, Isidoro; Wertz, Gail W (2005) Biological differences between vesicular stomatitis virus Indiana and New Jersey serotype glycoproteins: identification of amino acid residues modulating pH-dependent infectivity. J Virol 79:3578-85

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