Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI022839-11
Application #
2062007
Study Section
Bacteriology and Mycology Subcommittee 2 (BM)
Project Start
1985-12-01
Project End
1997-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
11
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Doherty, Timothy; Waring, Alan J; Hong, Mei (2006) Peptide-lipid interactions of the beta-hairpin antimicrobial peptide tachyplesin and its linear derivatives from solid-state NMR. Biochim Biophys Acta 1758:1285-91
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Tang, Ming; Waring, Alan J; Hong, Mei (2005) Intermolecular packing and alignment in an ordered beta-hairpin antimicrobial peptide aggregate from 2D solid-state NMR. J Am Chem Soc 127:13919-27
Mani, Rajeswari; Waring, Alan J; Lehrer, Robert I et al. (2005) Membrane-disruptive abilities of beta-hairpin antimicrobial peptides correlate with conformation and activity: a 31P and 1H NMR study. Biochim Biophys Acta 1716:11-8
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Buffy, Jarrod J; McCormick, Melissa J; Wi, Sungsool et al. (2004) Solid-state NMR investigation of the selective perturbation of lipid bilayers by the cyclic antimicrobial peptide RTD-1. Biochemistry 43:9800-12
Mani, Rajeswari; Buffy, Jarrod J; Waring, Alan J et al. (2004) Solid-state NMR investigation of the selective disruption of lipid membranes by protegrin-1. Biochemistry 43:13839-48
Owen, S M; Rudolph, D; Wang, W et al. (2004) A theta-defensin composed exclusively of D-amino acids is active against HIV-1. J Pept Res 63:469-76
Wang, Wei; Owen, Sherry M; Rudolph, Donna L et al. (2004) Activity of alpha- and theta-defensins against primary isolates of HIV-1. J Immunol 173:515-20
Munk, Carsten; Wei, Ge; Yang, Otto O et al. (2003) The theta-defensin, retrocyclin, inhibits HIV-1 entry. AIDS Res Hum Retroviruses 19:875-81

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