Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37AI027044-15
Application #
6550854
Study Section
Special Emphasis Panel (NSS)
Program Officer
Baker, Phillip J
Project Start
1993-12-01
Project End
2008-05-31
Budget Start
2003-06-01
Budget End
2004-05-31
Support Year
15
Fiscal Year
2003
Total Cost
$338,625
Indirect Cost
Name
State University New York Stony Brook
Department
Genetics
Type
Schools of Medicine
DUNS #
804878247
City
Stony Brook
State
NY
Country
United States
Zip Code
11794
Coleman, James L; Toledo, Alvaro; Benach, Jorge L (2018) HtrA of Borrelia burgdorferi Leads to Decreased Swarm Motility and Decreased Production of Pyruvate. MBio 9:
Toledo, Alvaro; Huang, Zhen; Coleman, James L et al. (2018) Lipid rafts can form in the inner and outer membranes of Borrelia burgdorferi and have different properties and associated proteins. Mol Microbiol 108:63-76
Huang, Zhen; Toledo, Alvaro M; Benach, Jorge L et al. (2016) Ordered Membrane Domain-Forming Properties of the Lipids of Borrelia burgdorferi. Biophys J 111:2666-2675
Monzón, Javier D; Atkinson, Elizabeth G; Henn, Brenna M et al. (2016) Population and Evolutionary Genomics of Amblyomma americanum, an Expanding Arthropod Disease Vector. Genome Biol Evol 8:1351-60
Coleman, James L; Toledo, Alvaro; Benach, Jorge L (2016) Borrelia burgdorferi?HtrA: evidence for twofold proteolysis of outer membrane protein p66. Mol Microbiol 99:135-50
Toledo, Alvaro; Pérez, Alberto; Coleman, James L et al. (2015) The lipid raft proteome of Borrelia burgdorferi. Proteomics 15:3662-75
Katona, Laura I (2015) The Fur homologue BosR requires Arg39 to activate rpoS transcription in Borrelia burgdorferi and thereby direct spirochaete infection in mice. Microbiology 161:2243-55
Toledo, Alvaro; Monzón, Javier D; Coleman, James L et al. (2015) Hypercholesterolemia and ApoE deficiency result in severe infection with Lyme disease and relapsing-fever Borrelia. Proc Natl Acad Sci U S A 112:5491-6
Toledo, Alvaro; Benach, Jorge L (2015) Hijacking and Use of Host Lipids by Intracellular Pathogens. Microbiol Spectr 3:
Toledo, Alvaro; Crowley, Jameson T; Coleman, James L et al. (2014) Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi. MBio 5:e00899-14

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