Agency
National Institute of Health (NIH)
Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37AI029470-14
Application #
6710180
Study Section
Special Emphasis Panel (NSS)
Program Officer
Mallia, Conrad M
Project Start
1990-12-01
Project End
2006-03-31
Budget Start
2004-04-01
Budget End
2005-03-31
Support Year
14
Fiscal Year
2004
Total Cost
$292,442
Indirect Cost
Name
University of California Los Angeles
Department
Microbiology/Immun/Virology
Type
Schools of Medicine
DUNS #
092530369
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Kim, Yun Cheol (2011) Introducing predetermined mutations throughout a target gene using TDEM (transposon-directed base-exchange mutagenesis). Methods Mol Biol 705:275-93
Yoo, Esther M; Yu, Li J; Wims, Letitia A et al. (2010) Differences in N-glycan structures found on recombinant IgA1 and IgA2 produced in murine myeloma and CHO cell lines. MAbs 2:320-34
Kim, Yun Cheol; Lee, Hui Sun; Yoon, Sukjoon et al. (2009) Transposon-directed base-exchange mutagenesis (TDEM): a novel method for multiple-nucleotide substitutions within a target gene. Biotechniques 46:534-42
Chintalacharuvu, Koteswara R; Gurbaxani, Brian; Morrison, Sherie L (2007) Incomplete assembly of IgA2m(2) in Chinese hamster ovary cells. Mol Immunol 44:3445-52
Beenhouwer, David O; Yoo, Esther M; Lai, Chun-Wei et al. (2007) Human immunoglobulin G2 (IgG2) and IgG4, but not IgG1 or IgG3, protect mice against Cryptococcus neoformans infection. Infect Immun 75:1424-35
Gurbaxani, Brian Mohan; Morrison, Sherie L (2006) Development of new models for the analysis of Fc-FcRn interactions. Mol Immunol 43:1379-89
Dela Cruz, Jay Soriano; Trinh, Kamh Ryan; Chen, Hsiao Wen et al. (2006) Anti-HER2/neu IgG3-(IL-2) and anti-HER2/neu IgG3-(GM-CSF) promote HER2/neu processing and presentation by dendritic cells: implications in immunotherapy and vaccination strategies. Mol Immunol 43:667-76
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Gurbaxani, Brian; Dela Cruz, Linh L; Chintalacharuvu, Koteswara et al. (2006) Analysis of a family of antibodies with different half-lives in mice fails to find a correlation between affinity for FcRn and serum half-life. Mol Immunol 43:1462-73
Zhu, Lei; van de Lavoir, Marie-Cecile; Albanese, Jenny et al. (2005) Production of human monoclonal antibody in eggs of chimeric chickens. Nat Biotechnol 23:1159-69

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