Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37DA007595-11
Application #
6335514
Study Section
Special Emphasis Panel (NSS)
Program Officer
Pollock, Jonathan D
Project Start
1992-01-10
Project End
2006-11-30
Budget Start
2002-02-20
Budget End
2002-11-30
Support Year
11
Fiscal Year
2002
Total Cost
$190,277
Indirect Cost

  Institution

Name
Oregon Health and Science University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
009584210
City
Portland
State
OR
Country
United States
Zip Code
97239

  Publications

Hong, Weimin Conrad; Yano, Hideaki; Hiranita, Takato et al. (2017) The sigma-1 receptor modulates dopamine transporter conformation and cocaine binding and may thereby potentiate cocaine self-administration in rats. J Biol Chem 292:11250-11261
Wheeler, David S; Underhill, Suzanne M; Stolz, Donna B et al. (2015) Amphetamine activates Rho GTPase signaling to mediate dopamine transporter internalization and acute behavioral effects of amphetamine. Proc Natl Acad Sci U S A 112:E7138-47
Underhill, Suzanne M; Wheeler, David S; Amara, Susan G (2015) Differential regulation of two isoforms of the glial glutamate transporter EAAT2 by DLG1 and CaMKII. J Neurosci 35:5260-70
Hong, Weimin C; Amara, Susan G (2013) Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons. FASEB J 27:2995-3007
Larsen, Mads Breum; Sonders, Mark S; Mortensen, Ole Valente et al. (2011) Dopamine transport by the serotonin transporter: a mechanistically distinct mode of substrate translocation. J Neurosci 31:6605-15
Hong, Weimin C; Amara, Susan G (2010) Membrane cholesterol modulates the outward facing conformation of the dopamine transporter and alters cocaine binding. J Biol Chem 285:32616-26
Fontana, Andréia C K; Sonders, Mark S; Pereira-Junior, Olavo S et al. (2009) Two allelic isoforms of the serotonin transporter from Schistosoma mansoni display electrogenic transport and high selectivity for serotonin. Eur J Pharmacol 616:48-57
Mortensen, Ole Valente; Larsen, Mads Breum; Prasad, Balakrishna M et al. (2008) Genetic complementation screen identifies a mitogen-activated protein kinase phosphatase, MKP3, as a regulator of dopamine transporter trafficking. Mol Biol Cell 19:2818-29
Mortensen, Ole V; Amara, Susan G (2006) Gain of function mutants reveal sites important for the interaction of the atypical inhibitors benztropine and bupropion with monoamine transporters. J Neurochem 98:1531-40
Mortensen, Ole V; Amara, Susan G (2003) Dynamic regulation of the dopamine transporter. Eur J Pharmacol 479:159-70

Showing the most recent 10 out of 32 publications