Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK031405-32
Application #
8477172
Study Section
Special Emphasis Panel (NSS)
Program Officer
Haft, Carol R
Project Start
1982-07-01
Project End
2014-06-30
Budget Start
2013-07-01
Budget End
2014-06-30
Support Year
32
Fiscal Year
2013
Total Cost
$660,464
Indirect Cost
$254,101
Name
Dana-Farber Cancer Institute
Department
Type
DUNS #
076580745
City
Boston
State
MA
Country
United States
Zip Code
02215
Zeng, Xing; Jedrychowski, Mark P; Chen, Yi et al. (2016) Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation. Genes Dev 30:1822-36
Svensson, Katrin J; Long, Jonathan Z; Jedrychowski, Mark P et al. (2016) A Secreted Slit2 Fragment Regulates Adipose Tissue Thermogenesis and Metabolic Function. Cell Metab 23:454-66
Chouchani, Edward T; Kazak, Lawrence; Jedrychowski, Mark P et al. (2016) Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1. Nature 532:112-6
Long, Jonathan Z; Svensson, Katrin J; Bateman, Leslie A et al. (2016) The Secreted Enzyme PM20D1 Regulates Lipidated Amino Acid Uncouplers of Mitochondria. Cell 166:424-35
Kir, Serkan; Komaba, Hirotaka; Garcia, Ana P et al. (2016) PTH/PTHrP Receptor Mediates Cachexia in Models of Kidney Failure and Cancer. Cell Metab 23:315-23
Banks, Alexander S; McAllister, Fiona E; Camporez, João Paulo G et al. (2015) An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ. Nature 517:391-5
Jedrychowski, Mark P; Wrann, Christiane D; Paulo, Joao A et al. (2015) Detection and Quantitation of Circulating Human Irisin by Tandem Mass Spectrometry. Cell Metab 22:734-40
Kazak, Lawrence; Chouchani, Edward T; Jedrychowski, Mark P et al. (2015) A creatine-driven substrate cycle enhances energy expenditure and thermogenesis in beige fat. Cell 163:643-55
Wahlqvist, Mark L; Krawetz, Stephen A; Rizzo, Nico S et al. (2015) Early-life influences on obesity: from preconception to adolescence. Ann N Y Acad Sci 1347:1-28
Long, Jonathan Z; Svensson, Katrin J; Tsai, Linus et al. (2014) A smooth muscle-like origin for beige adipocytes. Cell Metab 19:810-20

Showing the most recent 10 out of 87 publications