Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37DK032948-09
Application #
3483632
Study Section
Endocrinology Study Section (END)
Project Start
1990-09-01
Project End
1995-08-31
Budget Start
1990-09-01
Budget End
1991-08-31
Support Year
9
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Lu, Jianning; Luo, Ceng; Bali, Kiran Kumar et al. (2015) A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses. Nat Commun 6:6820
Puigdellívol, Mar; Cherubini, Marta; Brito, Verónica et al. (2015) A role for Kalirin-7 in corticostriatal synaptic dysfunction in Huntington's disease. Hum Mol Genet 24:7265-85
Miller, Megan B; Vishwanatha, Kurutihalli S; Mains, Richard E et al. (2015) An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions. J Biol Chem 290:13541-55
Yan, Yan; Eipper, Betty A; Mains, Richard E (2015) Kalirin-9 and Kalirin-12 Play Essential Roles in Dendritic Outgrowth and Branching. Cereb Cortex 25:3487-501
Mandela, Prashant; Yan, Yan; LaRese, Taylor et al. (2014) Elimination of Kalrn expression in POMC cells reduces anxiety-like behavior and contextual fear learning. Horm Behav 66:430-8
Ma, Xin-Ming; Miller, Megan B; Vishwanatha, K S et al. (2014) Nonenzymatic domains of Kalirin7 contribute to spine morphogenesis through interactions with phosphoinositides and Abl. Mol Biol Cell 25:1458-71
Huang, Su; Eleniste, Pierre P; Wayakanon, Kornchanok et al. (2014) The Rho-GEF Kalirin regulates bone mass and the function of osteoblasts and osteoclasts. Bone 60:235-45
Miller, Megan B; Yan, Yan; Eipper, Betty A et al. (2013) Neuronal Rho GEFs in synaptic physiology and behavior. Neuroscientist 19:255-73
Wu, Jiao-Hui; Fanaroff, Alexander C; Sharma, Krishn C et al. (2013) Kalirin promotes neointimal hyperplasia by activating Rac in smooth muscle cells. Arterioscler Thromb Vasc Biol 33:702-8
Gaier, E D; Eipper, B A; Mains, R E (2013) Copper signaling in the mammalian nervous system: synaptic effects. J Neurosci Res 91:2-19

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