Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37DK060596-17
Application #
9471818
Study Section
Special Emphasis Panel (NSS)
Program Officer
Maruvada, Padma
Project Start
2016-06-15
Project End
2021-04-30
Budget Start
2018-05-01
Budget End
2019-04-30
Support Year
17
Fiscal Year
2018
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Genetics
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Yadav, Vinita; Gao, Xing-Huang; Willard, Belinda et al. (2017) Hydrogen sulfide modulates eukaryotic translation initiation factor 2? (eIF2?) phosphorylation status in the integrated stress-response pathway. J Biol Chem 292:13143-13153
Ziosi, Marcello; Di Meo, Ivano; Kleiner, Giulio et al. (2017) Coenzyme Q deficiency causes impairment of the sulfide oxidation pathway. EMBO Mol Med 9:96-111
Roy, Debasish; Farabaugh, Kenneth T; Wu, Jing et al. (2017) Coordinated transcriptional control of adipocyte triglyceride lipase (Atgl) by transcription factors Sp1 and peroxisome proliferator-activated receptor ? (PPAR?) during adipocyte differentiation. J Biol Chem 292:14827-14835
Farabaugh, Kenneth T; Majumder, Mithu; Guan, Bo-Jhih et al. (2017) Protein Kinase R Mediates the Inflammatory Response Induced by Hyperosmotic Stress. Mol Cell Biol 37:
Krokowski, Dawid; Guan, Bo-Jhih; Wu, Jing et al. (2017) GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells. Cell Rep 21:2895-2910
Guan, Bo-Jhih; van Hoef, Vincent; Jobava, Raul et al. (2017) A Unique ISR Program Determines Cellular Responses to Chronic Stress. Mol Cell 68:885-900.e6
Davuluri, Gangarao; Krokowski, Dawid; Guan, Bo-Jhih et al. (2016) Metabolic adaptation of skeletal muscle to hyperammonemia drives the beneficial effects of l-leucine in cirrhosis. J Hepatol 65:929-937
Hsu, K-S; Guan, B-J; Cheng, X et al. (2016) Translational control of PML contributes to TNF?-induced apoptosis of MCF7 breast cancer cells and decreased angiogenesis in HUVECs. Cell Death Differ 23:469-83
Hao, Yujun; Samuels, Yardena; Li, Qingling et al. (2016) Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. Nat Commun 7:11971
Golovko, Andrei; Kojukhov, Artyom; Guan, Bo-Jhih et al. (2016) The eIF2A knockout mouse. Cell Cycle 15:3115-3120

Showing the most recent 10 out of 34 publications