Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37EY000444-28
Application #
2157925
Study Section
Special Emphasis Panel (NSS)
Project Start
1976-12-01
Project End
1996-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
28
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Mukherjee, Pranab K; Marcheselli, Victor L; Barreiro, Sebastian et al. (2007) Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling. Proc Natl Acad Sci U S A 104:13152-7
Ruiz, Alberto; Ghyselinck, Norbert B; Mata, Nathan et al. (2007) Somatic ablation of the Lrat gene in the mouse retinal pigment epithelium drastically reduces its retinoid storage. Invest Ophthalmol Vis Sci 48:5377-87
Bok, Dean (2007) Contributions of genetics to our understanding of inherited monogenic retinal diseases and age-related macular degeneration. Arch Ophthalmol 125:160-4
Mora, Rosalia C; Bonilha, Vera L; Shin, Bo-Chul et al. (2006) Bipolar assembly of caveolae in retinal pigment epithelium. Am J Physiol Cell Physiol 290:C832-43
Senanayake, Preenie deS; Calabro, Anthony; Hu, Jane G et al. (2006) Glucose utilization by the retinal pigment epithelium: evidence for rapid uptake and storage in glycogen, followed by glycogen utilization. Exp Eye Res 83:235-46
Radu, Roxana A; Han, Yun; Bui, Tam V et al. (2005) Reductions in serum vitamin A arrest accumulation of toxic retinal fluorophores: a potential therapy for treatment of lipofuscin-based retinal diseases. Invest Ophthalmol Vis Sci 46:4393-401
Deora, Ami A; Philp, Nancy; Hu, Jane et al. (2005) Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia. Proc Natl Acad Sci U S A 102:16245-50
Rohrer, Baerbel; Blanco, Roman; Marc, Robert E et al. (2004) Functionally intact glutamate-mediated signaling in bipolar cells of the TRKB knockout mouse retina. Vis Neurosci 21:703-13
Deora, Ami A; Gravotta, Diego; Kreitzer, Geri et al. (2004) The basolateral targeting signal of CD147 (EMMPRIN) consists of a single leucine and is not recognized by retinal pigment epithelium. Mol Biol Cell 15:4148-65
Stamer, W Daniel; Bok, Dean; Hu, Jane et al. (2003) Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement. Invest Ophthalmol Vis Sci 44:2803-8

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