Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM018926-32
Application #
6627096
Study Section
Special Emphasis Panel (NSS)
Program Officer
Wolfe, Paul B
Project Start
1976-01-01
Project End
2004-12-31
Budget Start
2003-01-01
Budget End
2003-12-31
Support Year
32
Fiscal Year
2003
Total Cost
$503,696
Indirect Cost
Name
University of Washington
Department
Genetics
Type
Schools of Medicine
DUNS #
605799469
City
Seattle
State
WA
Country
United States
Zip Code
98195
Brewer, Bonita J; Payen, Celia; Di Rienzi, Sara C et al. (2015) Origin-Dependent Inverted-Repeat Amplification: Tests of a Model for Inverted DNA Amplification. PLoS Genet 11:e1005699
Payen, Celia; Di Rienzi, Sara C; Ong, Giang T et al. (2014) The dynamics of diverse segmental amplifications in populations of Saccharomyces cerevisiae adapting to strong selection. G3 (Bethesda) 4:399-409
Liachko, Ivan; Youngblood, Rachel A; Tsui, Kyle et al. (2014) GC-rich DNA elements enable replication origin activity in the methylotrophic yeast Pichia pastoris. PLoS Genet 10:e1004169
Hiraga, Shin-Ichiro; Alvino, Gina M; Chang, Fujung et al. (2014) Rif1 controls DNA replication by directing Protein Phosphatase 1 to reverse Cdc7-mediated phosphorylation of the MCM complex. Genes Dev 28:372-83
Kwan, Elizabeth X; Foss, Eric J; Tsuchiyama, Scott et al. (2013) A natural polymorphism in rDNA replication origins links origin activation with calorie restriction and lifespan. PLoS Genet 9:e1003329
Pohl, Thomas J; Kolor, Katherine; Fangman, Walton L et al. (2013) A DNA sequence element that advances replication origin activation time in Saccharomyces cerevisiae. G3 (Bethesda) 3:1955-63
Di Rienzi, Sara C; Lindstrom, Kimberly C; Mann, Tobias et al. (2012) Maintaining replication origins in the face of genomic change. Genome Res 22:1940-52
Di Rienzi, Sara C; Lindstrom, Kimberly C; Lancaster, Ragina et al. (2011) Genetic, genomic, and molecular tools for studying the protoploid yeast, L. waltii. Yeast 28:137-51
Brewer, Bonita J; Payen, Celia; Raghuraman, M K et al. (2011) Origin-dependent inverted-repeat amplification: a replication-based model for generating palindromic amplicons. PLoS Genet 7:e1002016