Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
5R37GM018974-25
Application #
2173405
Study Section
Special Emphasis Panel (NSS)
Project Start
1975-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
25
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Bruzzone, R; White, T W; Paul, D L (1994) Expression of chimeric connexins reveals new properties of the formation and gating behavior of gap junction channels. J Cell Sci 107 ( Pt 4):955-67
Bruzzone, R; White, T W; Scherer, S S et al. (1994) Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease. Neuron 13:1253-60
Musil, L S; Goodenough, D A (1993) Multisubunit assembly of an integral plasma membrane channel protein, gap junction connexin43, occurs after exit from the ER. Cell 74:1065-77
Bruzzone, R; Haefliger, J A; Gimlich, R L et al. (1993) Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins. Mol Biol Cell 4:7-20
Flint, K K; Rosbash, M; Hall, J C (1993) Transfer of dye among salivary gland cells is not affected by genetic variations of the period clock gene in Drosophila melanogaster. J Membr Biol 136:333-42
White, T W; Bruzzone, R; Goodenough, D A et al. (1992) Mouse Cx50, a functional member of the connexin family of gap junction proteins, is the lens fiber protein MP70. Mol Biol Cell 3:711-20
Harris, A L; Walter, A; Paul, D et al. (1992) Ion channels in single bilayers induced by rat connexin32. Brain Res Mol Brain Res 15:269-80
Musil, L S; Goodenough, D A (1991) Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J Cell Biol 115:1357-74
Swenson, K I; Piwnica-Worms, H; McNamee, H et al. (1990) Tyrosine phosphorylation of the gap junction protein connexin43 is required for the pp60v-src-induced inhibition of communication. Cell Regul 1:989-1002
Beyer, E C; Paul, D L; Goodenough, D A (1990) Connexin family of gap junction proteins. J Membr Biol 116:187-94

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