Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37GM034695-18
Application #
6384014
Study Section
Special Emphasis Panel (NSS)
Program Officer
Somers, Scott D
Project Start
1985-04-01
Project End
2007-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
18
Fiscal Year
2002
Total Cost
$539,823
Indirect Cost
Name
University of Medicine & Dentistry of NJ
Department
Surgery
Type
Schools of Medicine
DUNS #
622146454
City
Piscataway
State
NJ
Country
United States
Zip Code
08854
Kamisoglu, Kubra; Haimovich, Beatrice; Calvano, Steve E et al. (2015) Human metabolic response to systemic inflammation: assessment of the concordance between experimental endotoxemia and clinical cases of sepsis/SIRS. Crit Care 19:71
Kamisoglu, Kubra; Calvano, Steve E; Coyle, Susette M et al. (2014) Integrated transcriptional and metabolic profiling in human endotoxemia. Shock 42:499-508
Kamisoglu, Kubra; Sleight, Kirsten; Nguyen, Tung T et al. (2014) Effects of coupled dose and rhythm manipulation of plasma cortisol levels on leukocyte transcriptional response to endotoxin challenge in humans. Innate Immun 20:774-84
Haimovich, Beatrice; Zhang, Zhiyong; Calvano, Jacqueline E et al. (2014) Cellular metabolic regulators: novel indicators of low-grade inflammation in humans. Ann Surg 259:999-1006
Scheff, Jeremy D; Griffel, Benjamin; Corbett, Siobhan A et al. (2014) On heart rate variability and autonomic activity in homeostasis and in systemic inflammation. Math Biosci 252:36-44
Scheff, Jeremy D; Calvano, Steve E; Androulakis, Ioannis P (2013) Predicting critical transitions in a model of systemic inflammation. J Theor Biol 338:9-15
Mavroudis, P D; Scheff, J D; Calvano, S E et al. (2013) Systems biology of circadian-immune interactions. J Innate Immun 5:153-62
Scheff, Jeremy D; Mavroudis, Panteleimon D; Calvano, Steve E et al. (2013) Translational applications of evaluating physiologic variability in human endotoxemia. J Clin Monit Comput 27:405-15
Kamisoglu, Kubra; Sleight, Kirsten E; Calvano, Steve E et al. (2013) Temporal metabolic profiling of plasma during endotoxemia in humans. Shock 40:519-26
Nguyen, Tung T; Calvano, Steve E; Lowry, Stephen F et al. (2013) An agent-based model of cellular dynamics and circadian variability in human endotoxemia. PLoS One 8:e55550

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