Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
2R37HL016512-15
Application #
3485494
Study Section
Nutrition Study Section (NTN)
Project Start
1979-05-01
Project End
1994-04-30
Budget Start
1989-05-01
Budget End
1990-04-30
Support Year
15
Fiscal Year
1989
Total Cost
Indirect Cost
Name
Baylor College of Medicine
Department
Type
Schools of Medicine
DUNS #
074615394
City
Houston
State
TX
Country
United States
Zip Code
77030
Kojima, Hideto; Fujimiya, Mineko; Matsumura, Kazuhiro et al. (2004) Extrapancreatic insulin-producing cells in multiple organs in diabetes. Proc Natl Acad Sci U S A 101:2458-63
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Oka, Kazuhiro; Chan, Lawrence (2004) Liver-directed gene therapy for dyslipidemia and diabetes. Curr Atheroscler Rep 6:203-9
Kojima, Hideto; Fujimiya, Mineko; Matsumura, Kazuhiro et al. (2003) NeuroD-betacellulin gene therapy induces islet neogenesis in the liver and reverses diabetes in mice. Nat Med 9:596-603
Belalcazar, L Maria; Merched, Aksam; Carr, Boyd et al. (2003) Long-term stable expression of human apolipoprotein A-I mediated by helper-dependent adenovirus gene transfer inhibits atherosclerosis progression and remodels atherosclerotic plaques in a mouse model of familial hypercholesterolemia. Circulation 107:2726-32
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Chan, Lawrence; Fujimiya, Mineko; Kojima, Hideto (2003) In vivo gene therapy for diabetes mellitus. Trends Mol Med 9:430-5
Serhan, Charles N; Jain, Ashish; Marleau, Sylvie et al. (2003) Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. J Immunol 171:6856-65
Merched, Aksam J; Williams, Elizabeth; Chan, Lawrence (2003) Macrophage-specific p53 expression plays a crucial role in atherosclerosis development and plaque remodeling. Arterioscler Thromb Vasc Biol 23:1608-14
Ma, Ke; Cilingiroglu, Mehmet; Otvos, James D et al. (2003) Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proc Natl Acad Sci U S A 100:2748-53

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