Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Method to Extend Research in Time (MERIT) Award (R37)
Project #
4R37HL028028-19
Application #
2825107
Study Section
Special Emphasis Panel (NSS)
Project Start
1982-01-01
Project End
2004-12-31
Budget Start
2000-03-15
Budget End
2000-12-31
Support Year
19
Fiscal Year
2000
Total Cost
$435,725
Indirect Cost
Name
Johns Hopkins University
Department
Pediatrics
Type
Schools of Medicine
DUNS #
045911138
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Keefer, Jeffrey R; Schneidereith, Tonya A; Mays, Abbie et al. (2006) Role of cyclic nucleotides in fetal hemoglobin induction in cultured CD34+ cells. Exp Hematol 34:1151-61
Resar, Linda M S; Segal, Jodi B; Fitzpatric, Lorna K et al. (2002) Induction of fetal hemoglobin synthesis in children with sickle cell anemia on low-dose oral sodium phenylbutyrate therapy. J Pediatr Hematol Oncol 24:737-41
Chang, Y P; Maier-Redelsperger, M; Smith, K D et al. (1997) The relative importance of the X-linked FCP locus and beta-globin haplotypes in determining haemoglobin F levels: a study of SS patients homozygous for beta S haplotypes. Br J Haematol 96:806-14
Bridges, K R; Barabino, G D; Brugnara, C et al. (1996) A multiparameter analysis of sickle erythrocytes in patients undergoing hydroxyurea therapy. Blood 88:4701-10
Chang, Y C; Smith, K D; Moore, R D et al. (1995) An analysis of fetal hemoglobin variation in sickle cell disease: the relative contributions of the X-linked factor, beta-globin haplotypes, alpha-globin gene number, gender, and age. Blood 85:1111-7
Collins, A F; Pearson, H A; Giardina, P et al. (1995) Oral sodium phenylbutyrate therapy in homozygous beta thalassemia: a clinical trial. Blood 85:43-9
Chang, Y P; Smith, K D; Dover, G J (1994) Dinucleotide repeat polymorphisms at the DXS85, DXS16 and DXS43 loci. Hum Mol Genet 3:1029
Stamatoyannopoulos, G; Blau, C A; Nakamoto, B et al. (1994) Fetal hemoglobin induction by acetate, a product of butyrate catabolism. Blood 84:3198-204
Dover, G J; Brusilow, S; Charache, S (1994) Induction of fetal hemoglobin production in subjects with sickle cell anemia by oral sodium phenylbutyrate. Blood 84:339-43
Dover, G J; Smith, K D; Chang, Y C et al. (1992) Fetal hemoglobin levels in sickle cell disease and normal individuals are partially controlled by an X-linked gene located at Xp22.2. Blood 80:816-24

Showing the most recent 10 out of 20 publications