Computer Vision Syndrome (CVS) refers to a collection of eye problems associated with computer use, and about three-quarters of computer users have it. Conservative estimates indicate that over $2 billion is currently spent on examinations and special eyewear for CVS treatment. The most common symptoms of CVS include: eyestrain or eye fatigue, dry eyes, burning eyes, sensitivity to light, and blurred vision. Non-ocular symptoms include headaches, pain in the shoulders, neck, or back. As diverse as the symptoms are, they may be related and can be subdivided into to three potential pathophysiological causes: ? 1) Ocular Surface Mechanisms ? 2) Accommodative Mechanisms ? 3) Extra-Ocular Mechanisms ? There is a significant gap in the fund of knowledge regarding the diagnosis of this disease. In the near-term, we plan to focus on the ocular surface category of disorders as a cause of CVS, identify clinical conditions associated with this syndrome and develop a treatment that addresses this cause. In phase 1, we propose to: ? Clinically define CVS by observing the incidence of ocular surface abnormalities in symptomatic subjects and compare them with an age and sex matched non-symptomatic control population ? Develop specialized micro-environment glasses to combat CVS symptoms ? Study the efficacy of micro-environment glasses in symptomatic and control populations ? Critically evaluate viability of CVS micro-environment glasses as a commercial product ? using both statistical methods and subjective questionnaires. ? ? ?

Agency
National Institute of Health (NIH)
Institute
National Eye Institute (NEI)
Type
Small Business Technology Transfer (STTR) Grants - Phase I (R41)
Project #
1R41EY015023-01A1
Application #
6792878
Study Section
Special Emphasis Panel (ZRG1-DBD (10))
Program Officer
Helmsen, Ralph J
Project Start
2004-09-30
Project End
2007-08-31
Budget Start
2004-09-30
Budget End
2007-08-31
Support Year
1
Fiscal Year
2004
Total Cost
$100,000
Indirect Cost
Name
Seefit, Inc.
Department
Type
DUNS #
171209344
City
Houston
State
TX
Country
United States
Zip Code
77005
Yee, Richard W; Sperling, Harry G; Kattek, Ashballa et al. (2007) Isolation of the ocular surface to treat dysfunctional tear syndrome associated with computer use. Ocul Surf 5:308-15