Over the last decade, death from drug overdose has created an epidemic across the United States. In 2017, there were 70,237 deaths from drug overdose, including 47,600 deaths involving opioids?a 12% increase from previous opioid overdose deaths [1]. While overdoses related to prescription opioids have decreased, synthetic opioids made up over half of all opioid-related overdose deaths and increased over 40% from the prior year [1]. The goal in this proposal is closely aligned with the mission of the National Institute of Drug Abuse (NIDA) to educate clinical providers and lay people towards improving treatment and outcomes for those suffering from substance use disorders (SUDs), specifically in response to a drug overdose. Many barriers have been identified for training providers on SUDs [2, 3]. Simulation-based training has shown promise for training providers about responding to drug overdose during Basic Life Support (BLS) training [4]. However, simulation-based training is resource intensive and can be difficult to implement as current simulator technologies require facilities, staff, and technology support. Overdose education and naloxone distribution (OEND) is associated with improved outcomes for people experiencing opioid overdose as well as decreased drug use by people who participated in OEND programs [5-11]. Increasing access to OEND could expand these positive results. The goal of this Phase I SBIR is to develop and integrate a curriculum for OEND using Lumis?s existing augmented reality (AR) healthcare simulator, the InSight Platform. The InSight Platform incorporates knowledge-based and hands-on training, requires less resources than traditional simulation, and supports broad deployment. The proposed curriculum will include a series of opioid overdose scenarios demonstrating patients in various stages of depressed level of consciousness and physiologic deterioration. These scenarios will allow clinical providers and lay people to train for evaluation, diagnosis, and treatment of an opioid overdose with naloxone. Integrating the proposed curriculum for knowledge-based and hands-on training into the InSight Platform has the potential to rapidly and broadly disseminate standardized OEND curriculum. Mixed methods research will: (1) develop and refine a curriculum for providers and patients through structured interviews with subject matter experts (SMEs), (2) integrate curriculum into Lumis? software with iterative feedback from SMEs throughout the process, and (3) evaluate feasibility, usability, and initial learning efficacy through focus groups and training sessions with facility administrators, clinical providers, and lay people.

Public Health Relevance

Overdose education and naloxone distribution (OEND) programs show promise towards reducing overdose deaths related to opioids as well as reducing use of drugs by users. OEND programs use patient simulators for hands-on training of cardiopulmonary resuscitation (CPR), but current systems lack the capability for training hands-on administration of naloxone during complex overdose scenarios. The goal of this Phase I SBIR is to develop and integrate a curriculum and hands-on training for complex overdose scenarios, including naloxone injection, using Lumis?s existing augmented reality (AR) healthcare simulator, the InSight Platform, for rapid deployment in the field for training to directly save lives.

Agency
National Institute of Health (NIH)
Institute
National Institute on Drug Abuse (NIDA)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43DA050371-01
Application #
9906749
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Angelone, Leonardo Maria
Project Start
2019-09-15
Project End
2020-06-30
Budget Start
2019-09-15
Budget End
2020-06-30
Support Year
1
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Lumis Corp.
Department
Type
DUNS #
081330707
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213