The specific aim of the proposed work is to demonstrate and improve a safe air enema technique for non fluoroscopy treatment of intussusception in children and to develop a novel single-chip microprocessor-based instrument for real-time on-site assessment of the result of the air enema treatment. The investigators' approach will employ the pressure sensing, density sensing, and sound sensing techniques, with microprocessor close-loop feedback. Three significant symptoms the occurrence of the recanalization of sound, the drop in inter-colon pressure, and the disappearance of abdominal mass detected by their novel instrument will be used to indicate the success of the treatment. The success of the proposed work will provide pediatricians with a unique means for the management of intussusception in infants and young children. The new method is non-invasive and nonfluoroscopic will avoid the harmful x-ray radiation and eliminate the chance of fatal accidents such as colonic perforations, thus is extremely safe in comparison with the previous methods. The other advantages of the new technique include simpler operation, substantially shorter recovery time, no complications, no anesthesia required, and lower cost.

Agency
National Institute of Health (NIH)
Institute
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43DK043178-01
Application #
3496025
Study Section
Surgery and Bioengineering Study Section (SB)
Project Start
1990-09-30
Project End
1991-03-31
Budget Start
1990-09-30
Budget End
1991-03-31
Support Year
1
Fiscal Year
1990
Total Cost
Indirect Cost
Name
Martin Goffman Associates
Department
Type
DUNS #
City
Edison
State
NJ
Country
United States
Zip Code
08820