Intelligent Optical Systems, Inc. (lOS) proposes to develop an innovative, optical fiber probe, or optode, that will improve collection efficiency of the probe by an order of magnitude and improve the sensitivity of target molecule sensing and imaging devices in medical applications. By fabricating submicron structures in glass, we will enhance optical signals in microcavity structure optodes. The proposed approach combines the usual fluorescent fiber optode detector with two new techniques: microcavity structures and alternating index clad fiber. This optode design increases the amount of light seen by the detector. Such an effect is achieved by the ability of periodic dielectric microcavity structures to modify the radiation properties of light inside the structure.

Agency
National Institute of Health (NIH)
Institute
National Institute of Biomedical Imaging and Bioengineering (NIBIB)
Type
Small Business Innovation Research Grants (SBIR) - Phase I (R43)
Project #
1R43EB000976-01
Application #
6645229
Study Section
Special Emphasis Panel (ZRG1-SSS-7 (10))
Program Officer
Korte, Brenda
Project Start
2003-04-01
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2005-03-31
Support Year
1
Fiscal Year
2003
Total Cost
$126,327
Indirect Cost
Name
Intelligent Optical Systems, Inc.
Department
Type
DUNS #
033449757
City
Torrance
State
CA
Country
United States
Zip Code
90505