Alzheimer's disease is a neurodegenerative disease of the brain causing impairments to memory and cognitive functions, eventually leading to death. The causes of Alzheimer's disease and mechanisms of disease progression are not fully understood, but an enormous amount of effort is being focused on the issues in research and pharmacologic interventions. Brain Image Analysis, LLC has developed NeuroAnalytica to provide high quality brain morphometry measures for biomarkers in Alzheimer's disease. This Phase II project will expand the basic measures to include a wide range of modalities and measures that research has shown to be useful in as potential biomarkers in Alzheimer's disease.

Public Health Relevance

Alzheimer's disease is a neurodegenerative disease of the brain causing impairments to memory and cognitive functions, eventually leading to death. The causes of Alzheimer's disease and mechanisms of disease progression are not fully understood, but an enormous amount of effort is being focused on the issues in research and pharmacologic interventions. Brain Image Analysis, LLC has developed NeuroAnalytica to provide high quality brain morphometry measures for biomarkers in Alzheimer's disease. This Phase II project will expand the basic measures to include a wide range of modalities and measures that research has shown to be useful in as potential biomarkers in Alzheimer's disease.

Agency
National Institute of Health (NIH)
Institute
National Institute on Aging (NIA)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
2R44AG043298-03A1
Application #
8782370
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Hsiao, John
Project Start
2012-08-15
Project End
2017-06-30
Budget Start
2014-08-01
Budget End
2015-06-30
Support Year
3
Fiscal Year
2014
Total Cost
Indirect Cost
Name
Pierson Brain Image Analysis
Department
Type
DUNS #
City
Coralville
State
IA
Country
United States
Zip Code
52241