It is hypothesized that the use robotic rehabilitation tables coupled with virtual reality games with elderly stroke survivors residents in skilled nursin facilities (SNFs) will: 1) improve and maintain upper extremity uni-manual and bimanual function, reach, strength and ADL independence;2) improve and maintain cognition (memory, focus, problem solving);and 3) provide emotive uplifting and maintain it. This implements an integrative, single-point-of-care safe rehabilitation approach. The objectives of the project are 1 to develop a novel uni-manual and bimanual training device that is cheaper and safer than rehabilitation robots;2) a virtual reality-based adaptable and integrative maintenance program that is clinically effective and engaging for elderly stroke survivors and other patient population.
SPECIFIC AIMS 1) to develop the BrightArm Duo system for improving arm/shoulder motion range, shoulder strength, endurance, grasp strength, bimanual function and ADL independence, short-term memory, focusing, executive function and reduce depression in SNF residents chronic post-stroke;2) to evaluate the new system for rehabilitation and maintenance therapy through a multi-site, longitudinal, randomized controlled study of stroke survivors over a 12 month period. METHODS 1) Construct the BrightArm Duo system by designing and building a new tracking work surface and computerized forearm supports;2) Develop custom rehabilitation games that incorporate uni- and bimanual motor and cognitive training elements and automatically adapt to each patient. The games should combine to induce >350 repetitions/session;3) Develop a secure web-accessible database module for game data storage and analysis and ability to play against residents in other SNFs. Data will be sampled transparently in real time during play and uploaded to BCI clinical server;4) Usability study with healthy elderly adults, to uncover technical problems;5) Longitudinal, multi-site randomized controlled study with elderly stroke survivors that are residents at two SNFs in New Jersey. Subjects will be randomized into a control group (N=16) and an experimental group (N=32). The control group will continue with existing health maintenance programs. The experimental group will have existing maintenance program plus an additional 8 week initial intensive training, followed by periodic """"""""booster"""""""" rehabilitation sessions. All subjects will have multiple evaluations by blinded clinicians for physical and cognitive/emotive function. Existing maintenance programs at the two facilities will be documented in administration to all study participants. The experimental group will rate the BrightArm Duo therapy usefulness and gained independence in ADLs. NIH

Public Health Relevance

A new device and therapeutic/maintenance method for uni/bimanual arm rehabilitation and cognition/emotive therapy in a single-point-of-care. The approach can be extended to other patient populations with motor and cognitive co-morbidities acute, sub-acute and chronic, adult and paediatric.

National Institute of Health (NIH)
National Institute on Aging (NIA)
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
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Musculoskeletal Rehabilitation Sciences Study Section (MRS)
Program Officer
Chen, Wen G
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Bright Cloud International Corporation
Highland Park
United States
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House, Gregory; Burdea, Grigore; Polistico, Kevin et al. (2016) A Rehabilitation First-Tournament Between Teams of Nursing Home Residents with Chronic Stroke. Games Health J 5:75-83
House, G; Burdea, G; Polistico, K et al. (2016) Integrative rehabilitation of residents chronic post-stroke in skilled nursing facilities: the design and evaluation of the BrightArm Duo. Disabil Rehabil Assist Technol 11:683-94
Burdea, Grigore; Polistico, Kevin; Krishnamoorthy, Amalan et al. (2015) Feasibility study of the BrightBrainerâ„¢ integrative cognitive rehabilitation system for elderly with dementia. Disabil Rehabil Assist Technol 10:421-32
Burdea, Grigore C; Polistico, Kevin; House, Gregory P et al. (2015) Novel integrative virtual rehabilitation reduces symptomatology of primary progressive aphasia - a case report. Int J Neurosci 125:949-58