The overall goal of this Fast Track project is to combine innovations in superconducting magnet design and new developments in solid state MRI to create a highly compact, robust, mobile, lightweight, and affordable MRI for scanning the peripheral skeleton, including the knee, of the majority of the public. This scanner will use a unique, cryogen-free 3-bore actively shielded superconducting magnet that makes the scanner a realistic """"""""point-of- care"""""""" device that can be installed in smaller clinics, or even a doctor's office. The proposed scanner uses an innovative magnet design that allows the patient to have both legs comfortably stretched out into two separate warm bores of magnet. The combination of proven technologies in design and manufacturing of high-field (1.5T and higher) cryogen-free MRI magnets and the innovative 3-bore scanner will provide a significant breakthrough in providing a versatile, realistic point-of-care 1.5 T knee-accessible extremity MRI to the aging public.

Public Health Relevance

The Division of Geriatrics and Clinical Gerontology (DGCG) of the National Institute on Aging (NIA) is calling for the Development and validation of non-invasive methods of examining bone quality (density, architecture, and strength of bone), listed under area of interest G of DGCG research topics. Recent studies have shown the utility of MRI in addressing several factors related to bone quality. The overall goal of this project, Phase I and II combined, is to combine innovation in superconducting magnet design and new developments in solid state MRI to create a highly compact, robust, mobile, lightweight, cryogen-free, and affordable MRI for scanning the peripheral skeleton, including the knee, of the majority of the public.

Agency
National Institute of Health (NIH)
Institute
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Type
Small Business Innovation Research Grants (SBIR) - Phase II (R44)
Project #
1R44AR065903-01
Application #
8648022
Study Section
Special Emphasis Panel (ZRG1-SBIB-T (10))
Program Officer
Wang, Xibin
Project Start
2014-06-01
Project End
2014-11-30
Budget Start
2014-06-01
Budget End
2014-11-30
Support Year
1
Fiscal Year
2014
Total Cost
$211,444
Indirect Cost
Name
Superconducting Systems, Inc
Department
Type
DUNS #
124949699
City
Billerica
State
MA
Country
United States
Zip Code
01821
Cohen, Ouri; Ackerman, Jerome L (2018) Ex vivo mouse brain microscopy at 15T with loop-gap RF coil. Magn Reson Imaging 51:1-6