Youth suicide is a serious public health problem and clinical challenge for medical and behavioral health providers. Yet few preventive interventions have been tested for this population. This project addresses this deficit by testing the efficacy of a brief family therapy for adolescents presenting with serious risk for suicide in a primary care setting. Several innovations characterize the study. First, patients will be identified and treated directly in the primary care setting. Integrating behavioral health services into primary care may a) reduce burden on physicians by promoting parents as safety monitors, b) increase behavioral health treatment adherence, and c) address many underlying family problems associated with suicide. Second, to identify seriously at risk adolescents, we will assess for severe and persistent suicidal ideation and cooccurring depression. Patients will need to score above clinical cutoffs on both ideation (SIQ > 31) and depression (BDI-II >20) at two consecutive appointments (generally within 3 days of each other). Third, treatment will target two of the most critical suicide risk factors: depression and family conflict. Depression is the most consistently associated risk factor for suicide and family conflict is the most common precipitant of completed suicide (20%) and non-fatal suicidal episodes (50%). Fourth, we will use Attachment Based Family Therapy (ABFT; Diamond et al., 2002) as the intervention approach, an efficacious and manualized family therapy model specifically designed for adolescent depression. ABFT has been successful in reducing suicidal ideation, hopelessness, depression, anxiety, and family conflict. The Children's Hospital of Philadelphia's Adolescent Care Center will be the performance site, where typically 1 to 3 adolescents a week present with severe and current ideation. Eighty-seven percent of patients are African American and 60% are girls. One-hundred and twenty adolescents will be randomized to 6 to 10 weeks of either ABFT or Enhanced Usual Care (EUC). Patients will be evaluated at baseline 6, 12, 24, and 52 weeks.

Agency
National Institute of Health (NIH)
Institute
National Center for Injury Prevention and Control (NCIPC)
Type
Injury Control Research and Demonstration Projects and Injury Prevention Research Centers (R49)
Project #
1R49CE000428-01
Application #
6870756
Study Section
National Center for Injury Prevention and Control Initial Review Group (SCE)
Program Officer
Smutz, Paul
Project Start
2004-09-01
Project End
2007-08-31
Budget Start
2004-09-01
Budget End
2005-08-31
Support Year
1
Fiscal Year
2004
Total Cost
$300,000
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Bevans, Katherine B; Diamond, Guy; Levy, Suzanne (2012) Screening for adolescents' internalizing symptoms in primary care: item response theory analysis of the behavior health screen depression, anxiety, and suicidal risk scales. J Dev Behav Pediatr 33:283-90
Diamond, Guy S; Wintersteen, Matthew B; Brown, Gregory K et al. (2010) Attachment-based family therapy for adolescents with suicidal ideation: a randomized controlled trial. J Am Acad Child Adolesc Psychiatry 49:122-31
Diamond, Guy; Levy, Suzanne; Bevans, Katherine B et al. (2010) Development, validation, and utility of internet-based, behavioral health screen for adolescents. Pediatrics 126:e163-70
Sarwer, David B; Brown, Gregory K; Evans, Dwight L (2007) Cosmetic breast augmentation and suicide. Am J Psychiatry 164:1006-13