As one of the fastest growing Universities in the United States, Florida Atlantic University (FAU) recognizes the need to serve a diverse population. Situated in South Florida, a multi-cultural environment, FAU draws many of its students from the local community. As the higher education needs of the underrepresented minorities in the area grow, they will likely turn more and more to FAU to service those needs. To that end, FAU would like to develop competitive research programs that increase the number of underrepresented minorities professionally engaged in biomedical research. ? ? FAU is the most ethnically diverse institution in the State of Florida. The University community has more than 25,000 students and 900 faculty. Through its 8 colleges, FAU offers more than 170 baccalaureate, master's, and doctoral degree programs and conducts basic and applied research. Biomedical sciences is one of FAU's strategic themes, with a commitment to quality and cultural diversity. The FAU focus on biomedical sciences is represented by the 14 subprojects and 6 pilot subprojects in the present proposal. The research encompasses the Departments of Chemistry and Biochemistry, Biomedical Science, and Biological Sciences, and includes the synthesis or biosynthesis and characterization of novel therapeutics, understanding the basic mechanisms of tumor cell invasion, Sjogren's syndrome, cardiomyopathies, neuron survival in the olfactory system, RNA damage during oxidative stress, and lipid signaling in diet, microbiology/bioterrorism, and development of resonance Raman spectroscopy as a cellular probe. The majority of the investigators are junior faculty, and the SCORE Program would provide a tremendously important stepping stone in their research careers. For the more senior investigators, the Program would allow them to pursue new research areas or restart projects that had been slowed by substantial teaching assignments. The training of personnel would be substantial, and critical given the influx of biomedical employment opportunities to Palm Beach County. The MBRS SCORE Program would facilitate faculty development and training in all areas of biomedical research at a major minority serving institution. ? ?

Agency
National Institute of Health (NIH)
Institute
National Institute of General Medical Sciences (NIGMS)
Type
Minority Biomedical Research Support - MBRS (S06)
Project #
5S06GM073621-02
Application #
7075364
Study Section
Minority Programs Review Committee (MPRC)
Program Officer
Rivera-Rentas, Alberto L
Project Start
2005-06-08
Project End
2009-05-31
Budget Start
2006-06-01
Budget End
2007-05-31
Support Year
2
Fiscal Year
2006
Total Cost
$905,596
Indirect Cost
Name
Florida Atlantic University
Department
Chemistry
Type
Schools of Arts and Sciences
DUNS #
004147534
City
Boca Raton
State
FL
Country
United States
Zip Code
33431
Liu, Xiaoyan; Zhang, Lei; Pacciulli, Daniel et al. (2016) Restrictive Cardiomyopathy Caused by Troponin Mutations: Application of Disease Animal Models in Translational Studies. Front Physiol 7:629
Bionda, Nina; Pitteloud, Jean-Philippe; Cudic, Predrag (2013) Solid-phase synthesis of fusaricidin/LI-F class of cyclic lipopeptides: Guanidinylation of resin-bound peptidyl amines. Biopolymers 100:160-6
Bionda, Nina; Pitteloud, Jean-Philippe; Cudic, Predrag (2013) Cyclic lipodepsipeptides: a new class of antibacterial agents in the battle against resistant bacteria. Future Med Chem 5:1311-30
Li, Yuejin; Zhang, Lei; Jean-Charles, Pierre-Yves et al. (2013) Dose-dependent diastolic dysfunction and early death in a mouse model with cardiac troponin mutations. J Mol Cell Cardiol 62:227-36
Liu, Huan; Lu, Michael; Guthrie, Kathleen M (2013) Anterograde trafficking of neurotrophin-3 in the adult olfactory system in vivo. Exp Neurol 241:125-37
Alluri, Ravi K; Li, Zhongwei (2012) Novel one-step mechanism for tRNA 3'-end maturation by the exoribonuclease RNase R of Mycoplasma genitalium. J Biol Chem 287:23427-33
Bionda, Nina; Stawikowski, Maciej; Stawikowska, Roma et al. (2012) Effects of cyclic lipodepsipeptide structural modulation on stability, antibacterial activity, and human cell toxicity. ChemMedChem 7:871-82
Liu, Min; Gong, Xin; Alluri, Ravi Kumar et al. (2012) Characterization of RNA damage under oxidative stress in Escherichia coli. Biol Chem 393:123-32
Chen, G; Li, Y; Tian, J et al. (2012) Application of echocardiography on transgenic mice with cardiomyopathies. Biochem Res Int 2012:715197
Denz, Christopher R; Zhang, Chi; Jia, Pingping et al. (2011) Absence of mutation at the 5'-upstream promoter region of the TPM4 gene from cardiac mutant axolotl (Ambystoma mexicanum). Cardiovasc Toxicol 11:235-43

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