Chronopharmacological & Chronotherapeutic Investigation

Soliman, Magdi R I.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Center for Research Resources (NCRR)
• Type: Minority Biomedical Research Support Thematic Project Grants (S11)
• Project #: 5S11RR002660-04
• Application #: 3564543
• Study Section: General Research Support Program Advisory Committee (GRS)
• Project Start: 1985-09-30
• Project End: 1989-09-29
• Budget Start: 1988-09-30
• Budget End: 1989-09-29
• Support Year: 4
• Fiscal Year: 1988

Institution

• Name: Florida Agricultural and Mechanical University
• City: Tallahassee
• State: FL
• Country: United States
• Zip Code: 32307

Publications

Khan, M Omar F; Lee, Henry J (2008) Synthesis and pharmacology of anti-inflammatory steroidal antedrugs. Chem Rev 108:5131-45

Omar, M; Khan, F; Park, Kwan K et al. (2007) New steroidal anti-inflammatory antedrugs: 21-thioalkylether derivatives of methyl 16-prednisolone carboxylates. Med Chem 3:572-5

Park, Kwan-K; Ko, Dong-H; You, Z et al. (2006) In vitro anti-inflammatory activities of new steroidal antedrugs: [16alpha,17alpha-d] Isoxazoline and [16alpha,17alpha-d]-3'-hydroxy-iminoformyl isoxazoline derivatives of prednisolone and 9alpha-fluoroprednisolone. Steroids 71:183-8

Park, Kwan-Kyun; Ko, Dong-Hoon; You, Zhengqing et al. (2006) Synthesis and pharmacological evaluations of new steroidal anti-inflammatory antedrugs: 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-3,20-dioxo-pregna-1,4-diene-16alpha-carboxylate (FP16CM) and its derivatives. Steroids 71:83-9

You, Zhengqing; Lee, Henry Young (2006) New AZT conjugates as potent anti-HIV agents. Nucleosides Nucleotides Nucleic Acids 25:37-54

Khan, M Omar F; Park, Kwan K; Lee, Henry J (2005) Antedrugs: an approach to safer drugs. Curr Med Chem 12:2227-39

Park, Kwan-kyun; Ko, Dong-hoon; You, Zhengqing et al. (2004) Chirality effect of C-20 on metabolism of methyl 11beta,17alpha,20-trihydroxy-3-oxo-1,4-pregnadien-21-oate derivatives. Steroids 69:87-91

You, Zhengqing; Mian, A Moshin; Agarwal, Ram P et al. (2003) Synthesis, anti-HIV, and cytotoxic activity of new AZT conjugates of steroid acids. Nucleosides Nucleotides Nucleic Acids 22:2049-60

Park, Kwan-Kyun; Ko, Dong-Hoon; You, Zhengqing et al. (2003) Metabolism of steroidal anti-inflammatory antedrugs in vitro: methyl 3,20-dioxo-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-16alpha-carboxylate; its 9alpha-fluorinated, and their 21-O-acyl derivatives. Steroids 68:315-9

Ko, Dong-Hoon; Heiman, Ann S; Hudson, Charles E et al. (2002) New steroidal antiinflammatory antedrugs: Methyl 3,20-dioxo-9 alpha-fluoro-11 beta,17 alpha,21-trihydroxy-1,4-pregnadiene-16 alpha-carboxylate and its 21-O-acyl derivatives. Steroids 67:211-9