The Louisiana State University Health Sciences Center (LSUHSC) Biomedical Alcohol Research Training Program (BARTP) brings together outstanding pre- and postdoctoral fellows from diverse backgrounds (basic, clinical, public health, etc.) to train with an interdisciplinary group of scientists focused on studying the biomedical consequences of heavy or risky alcohol use, and specifically on their impact on comorbid conditions. Our holistic and integrative approach to professional development of our trainees provides opportunities for exploration and consideration of a wide range of career options in biomedical, healthcare, policy, and advocacy fields and uses personalized Individual Development Plans to guide each trainee?s experience. Primary and support faculty from the LSUHSC Schools of Medicine and Public Health, the Tulane University School of Public Health and Tropical Medicine, and the Tulane National Primate Research Center collaborate to provide interdisciplinary training and mentoring in diverse areas of alcohol research in addition to specialty training, including experimental design and statistical analysis, use of animals in research, and translational approaches. Trainees will pursue alcohol research projects under four interrelated themes: 1) Alcohol/HIV disease; 2) Neurobiology of alcohol use, abuse, and dependence; 3) Alcohol and comorbidities; and 4) Alcohol and the microbiome. Training and mentoring in a transdisciplinary environment with access to rodent and non-human primate models as well as clinical and translational studies provide a broad range of scientific areas for research training. Didactic and educational programs, including the study of responsible conduct of research, integrates pre- and postdoctoral trainee development. Participation in a professional development program designed to increase trainees? knowledge in the alcohol research field, experimental design and execution, data analysis, grantsmanship, and administrative and regulatory aspects necessary to conduct research is complemented with training and mentoring in written and oral communication skills to further their professional development. Five predoctoral trainees in the PhD or MD/PhD combined program, and four postdoctoral fellows (MD, DVM and/or PhD) will be recruited to the program each year. Particular emphasis is placed on recruitment of outstanding candidates from the combined MD/PhD program. Furthermore, efforts to continue recruitment, mentoring, and retention of fellows from diverse cultural, ethnic, and training backgrounds, particularly those that are underrepresented in the biomedical research field, will be emphasized. This program leverages and expands the scientific environment created by the NIAAA-funded LSUHSC Comprehensive Alcohol-HIV/AIDS Research Center (CARC).

Public Health Relevance

This training grant addresses the health needs of our nation by training the future generation of basic and translational scientists to address the major health concern of biomedical consequences of alcohol use disorders (AUDs). The World Health Organization estimates that alcohol contributes to more than 200 diseases and injury-related health conditions, and is the fifth leading risk factor for premature death and disability. Yearly in the US alone AUD adversely affects the lives of approximately 14 million Americans and their family members at a health care cost to society of greater than 249 billion dollars.

Agency
National Institute of Health (NIH)
Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Type
Institutional National Research Service Award (T32)
Project #
2T32AA007577-21
Application #
9717066
Study Section
Special Emphasis Panel (ZAA1)
Program Officer
Wang, Joe
Project Start
1999-09-22
Project End
2024-08-31
Budget Start
2019-09-01
Budget End
2020-08-31
Support Year
21
Fiscal Year
2019
Total Cost
Indirect Cost
Name
Louisiana State Univ Hsc New Orleans
Department
Physiology
Type
Schools of Medicine
DUNS #
782627814
City
New Orleans
State
LA
Country
United States
Zip Code
70112
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Pahng, Amanda R; Edwards, Scott (2018) Measuring Pain Avoidance-Like Behavior in Drug-Dependent Rats. Curr Protoc Neurosci 85:e53
Samuelson, Derrick R; Burnham, Ellen L; Maffei, Vincent J et al. (2018) The respiratory tract microbial biogeography in alcohol use disorder. Am J Physiol Lung Cell Mol Physiol 314:L107-L117
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Pahng, Amanda R; Colombo, Paul J (2017) Phosphorylation of tyrosine receptor kinase B in the dorsal striatum and dorsal hippocampus is associated with response learning in a water plus maze. Behav Neurosci 131:33-41
Pahng, Amanda R; McGinn, M Adrienne; Paulsen, Rod I et al. (2017) The Prefrontal Cortex as a Critical Gate of Negative Affect and Motivation in Alcohol Use Disorder. Curr Opin Behav Sci 13:139-143

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